Top similar games like Artificial Defense:

What if MOBAs and RTS games had a baby? Rover Wars combines resource management, farming, building and strategy into an intense tug of war. Fight in an interplanetary campaign and challenge your friends in the configurable Battle Mode. Rover Wars might be your gateway ticket into the strategy genre.

Slice them, burn them, skewer them, and launch them - no matter how you get it done, orcs must die in this fantasy action-strategy game from Robot Entertainment.

An epic, challenging tower defense game with an emphasis on strategy and replayability. Summon gems of immense magical potency and harness their unique abilities against a seemingly endless horde of monsters. The archdemon seeks to swallow the world, and you must journey to stand against her.

Fight off hordes of monstrous mutants created from a strange cataclysmic event in the new tower defense game, Prime World: Defenders. Join a group of exile treasure hunters who have ventured into the capital of an ancient empire, vast with mystery and danger.

Rocked by an explosive soundtrack, choose your band, place your equipments and defend the Rock 'N' Roll from everyone and everything who try to pull it down, on a totally hardcore tower defense!

Armoured Onslaught is a fast paced Top-Down Shooter and Tower Defence hybrid. You will need to make use of both strategy and skill as you fight your way through near endless hordes of deadly foes.

Do you like Tower Defense games with Strategy elements? Well, look no further! We've got exactly what you're looking for! Get ready to defend your settlement from enemies using a huge arsenal of towers!

Defense Grid: The Awakening is a unique spin on tower defense gameplay that will appeal to players of all skill levels. A horde of enemies is invading, and it's up to the player to stop them by strategically building fortification towers around their base.

Build up your fortifications, place your cannons, and fire at the enemy forces! Improve your Battle Haven with powerful upgrades while playing through a story campaign comprised of dozens of scenarios with unique mission types and multiple boss fights! Take to the sky and win!

Five-star tower defense with unrivaled depth and replayability. The Bloons are back in full HD glory and this time they mean business! Build awesome towers, choose your favorite upgrades, hire new Special Agents, and pop every last invading Bloon in the most popular tower defense series in history.

Bring your toys to life in this action-packed, Toy Soldiers game bundle which includes the original Toy Soldiers, Toy Soldiers: Cold War, and all four DLC’s – Kaiser’s Battle, Invasion, Napalm and Evil Empire.

You think Tower Defense games are all about building? You thought wrong. Sanctum is not your average Tower Defense title. When the havoc starts, you get to join the fray! As one of the world’s first First Person Shooter - Tower Defense games, Sanctum has taken the best of both worlds to deliver an epic, one-of-a-kind experience.

Tower defense reimagined! Dead Ground is a procedurally generated tower defense game with rogue-like elements. Each playthrough will offer randomly generated guns, skills and augments. You'll have to travel, collect scrap, water, manage your inventory and upgrade your base to survive!

The ultimate mash-up of Real-time Strategy and Tower Defense!

Creeper World 3 is what happens when cellular automata takes over a strategy simulation. Instead of discrete units that attack your base, a fluid-like substance spreads over the terraformable terrain. Your base, your weapons, your strategy... you must adapt them all.

Your castle is under attack! Defend your walls against enemies and epic bosses. Upgrade your defenses with unique weapons, strategic skills, and special upgrades! Become an unbeatable defender and master every battle.

Online Co-Operative Tower Defense with endless build options and a heavy focus on rewarding creative strategies. With so many Levels, Towers, Abilities, Items, & Builder Specialties every match can be a different experience!

A rock-solid combination of rock-rolling action, deep strategy, and captivating art and music from different ages of history, this is a game of crush or be crushed!

Anomaly 2 is a sequel to the critically acclaimed Anomaly Warzone Earth. Maintaining the core elements of the original, Anomaly 2 adds plenty of new features: unit morphing, over million tactical combinations, post-apo world and tower defense vs tower offense multiplayer mode.

Sanctum 2 is the sequel to the world’s first Tower Defense/FPS hybrid game. Pick from four unique character classes and embark on a mission to protect the oxygen-producing Cores from hordes of deadly aliens who are threatened by their existence.

Co-op and Single player Tower Defense genre.

Setting the bar as the definitive tower defense game, Defense Grid 2 introduces new worlds and threats to test your tower placement strategies. With a bold new look and the addition of new game modes, player-versus-player and multiplayer co-op, every play brings fun new opportunities and challenges.

Change your playground into a battlefield. Square off against an out-of-control 3D Printer with an army of your old-school toys, and stop the Plastic Rebellion!

Lead an armored squad through the perils of this reversed tower defense action-strategy game!

The greatest rock-racing, tower defense, art history game is back! Like the title says, Bigger & Boulder cranks up the surrealism and gameplay with chaotic 4P multiplayer, new time periods, and improved graphics, physics, and destructibility powered by UE4 to be, well… BIGGER AND BOULDER.

Fortified is an explosive strategy shooter where players will defend the Earth against a menacing Martian invasion in the 1950s. Play as one-of-four pulp inspired heroes as they fight swarms of terrifying robots with an arsenal of Cold War era weapons and experimental technology.

As a retired hero, lead and train your villagers to stand against relentless monster attacks. Assign roles, motivate your team, upgrade townsfolk, unlock powerful abilities, and adapt your strategy to outlast the next assault. TBH is a first-person fantasy action RPG with a strategy twist.

Mechs V Kaijus is an addictive hardcore tower defense gameplay. In Mechs V Kaijus you take on the role of Commander of a powerful Mechs squadron. Improve your Mech, strategically place towers and factories on the battlefield. Deploy support units on the battlefield, and save our civilization.

Taur is an action-strategy sci-fi game. Control the Prime Cannon and unlock all of its powerful weapons and abilities. Build turrets, droids, aircraft and more as you fight to protect the homeworld of the Tauron droids against a relentless invasion. Will your Taur stand against the Imperion warmachine?

Dungeon Defenders Eternity is the definitive version of the original tower defense action-RPG! Now featuring a rebalanced endgame, all new missions, secure online play, links to Dungeon Defenders II and more!

Rewrite history as you take control of the brutal Vikings, the devious Aztecs or the crafty Chinese in their global quest to win the favour of the Gods! Swords & Soldiers is a side-scrolling strategy game that lets you control an entire army and lets you wield devastating magical abilities.

ENDLESS™ Space 2 is a Strategic Space Opera, featuring the compelling “just one more turn” gameplay, set in the mysterious ENDLESS™ Universe. As the leader of your civilization, will you impose your vision and build the greatest stellar empire?

Immortal Defense is a story-driven tower defense game in which you give up your body and life to become an immortal "path defender", and defend your home world from destruction, forever. The game takes place over millions of years. Is there anything you would give up everything to defend?

A tactical auto-shooter where you build your own maze! Combine tower defense, roguelite powers, and upgrades to survive endless waves of monsters.