Top similar games like Immunity Protocol:

Chain of Command is a top-down arena shooter roguelike, where you control a snake-like chain of fighters that attack automatically. Choose your Commander and build your party to create high-synergy builds to crush the invading demon armies.

Survive the chaos of a bullet-heaven action game. Tear through enemy hordes, stack wild ability combos, and endure cataclysms that rewrite the rules mid-fight. The pace ramps up every minute - either you grow stronger, or you get wiped out.

Global Agent is a top-down roguelite action game in which you explore and save a world plunged into chaos by a mysterious plague. Step into the role of one of several agents, each of whom develops their own unique special abilities. Fight, plan your journey, and overcome the epidemic.

Blast your way through infinite hordes while completing objectives in this chaotic twin-stick looter shooter with frantic juicy combat. Upgrade gear, recruit heroes, tackle cumulative escalating challenges in your quest for the build of ultimate destruction.

Guide a brave bacteria to rescue his fiancée Zoe from the creatures of the immune system, using an arsenal of organic weapons and unique abilities.

Fast paced Top-down shooter! Smartly use IRCM to evade the constant barrage of bullets and missiles and destroy everything that stands in your way.

A sepia Roguelike — lead a chained squad through 22 waves. Map events split your line, milestone recruits add firepower. Linked Blink, run upgrades, 19 Evolutions, and a permanent meta tree carry you to the final Boss Hydra.

Fight through neon-drenched survival arenas as a cyber cat-eared gunslinger, stacking weapons, upgrades, and chaotic builds against overwhelming enemy swarms.

Survive the twilight or be consumed by it. A casual roguelite where every choice shapes your power — and thousands of creatures stand between you and dawn.

Cards and Guns is a top-down arena shooter roguelite, where you’ll have to defeat hordes of creatures. Choose from a variety of cards and upgrades to create unique builds and survive to the end.

The farm is under attack! Fight against an alien invasion as Hamdy, an armed scarecrow. In this top-down arena roguelike, build your loadout with up to 6 weapons, grow stronger after each wave, and survive until the very end.

Outlast wave after wave to grow unstoppable. Slimes Arena is a fast-paced arena shooter roguelite where each slime’s unique abilities combine with a wide variety of power-ups. No two runs are ever the same as you bounce to survive.

Gunclone Arena is a top-down looter-shooter roguelite. Fight as a super-clone that can wield 6 weapons, a Beam and Shield in a dystopian TV show! Loot thousands of weapon variants with ricochet, detonate, shock, pierce and more. Stack build-changing Mods. Notice: Escape is grounds for perma-recycle.

Crush, smash, and eat thousands of enemies showing humanity what the meaning of destruction is! Kaiju Catastrophe is an arcade game with roguelite mechanics. Mutate devastating weapons, unlock permanent evolutions, and wreak havoc with a variety of monsters to tear humanity apart!

Be the defender of innocence, the last remaining virtue in this land, and prevail against the evildoers! Sentinel of Innocence is a survival game with tower defense and rogue-lite elements.

Micron Survivor is a survival game with rogue-lite elements where you play as alien microorganisms under the microscope. Evolve, unlock research objectives, find symbiotic weapons, upgrade your builds, and fight hordes of terrestrial organisms to rule the microcosm.

Survive waves of wacky mutated constructs to defeat powerful bosses with your team of Plushie friends in this quirky chaotic Survivors-like. Earn merit badges to unlock new Plushies, relics, items, and upgrades.

Discover a short story where you will have to answer questions to overcome the challenges it presents. It is a mixture of bullet hell with hundreds of enemies and graphic adventure, where choices influence the plot.

Code of Shadows is a fast-paced real-time roguelite where you fight alongside powerful support drones. Pause on demand, evolve mid-fight, and push back relentless rift-spawned hordes across shifting dimensions. Adapt your build, master the chaos, and survive each run.

A fast-paced, intense top-down bullet hell action experience with a sci-fi aesthetic. As a protector of light, you must build your arsenal of weapons, abilities, reflexes, and wits as you slowly transform into an unstoppable force to survive through waves of monsters and demons from the void.

Blast through robotic hordes in this arena auto-battler rogue-lite Brotato-like. Use auto-firing weapons and drones, timely dashes and special abilities to reach the Void where a final Conservator awaits convergence. Spend your Cogs wisely within the varied shops to create unique builds!

QUANTUM HEART combines the thrill of dodging bullets in shoot 'em ups with the build variety of modern roguelikes. Graze enemy bullets to charge energy and unleash devastating powers. Take the elevator to the only city on Earth and depose the system that robbed your heart.

A fast-paced bullet heaven action roguelike set in a futuristic arena. Face overwhelming enemy waves, evolve your build with powerful upgrades, and survive escalating instability that constantly reshapes the battlefield.

Microbes and Machines is a roguelite action game where you control a little bubble robot that fights against the forces of evil.

A cyberpunk bullet-heaven roguelite. Survive the swarm, hack your kills, and turn enemy machines into your own weapons

Gran Theft Lure is a top-down arena shooter roguelite in which you play as your lovely gran being attacked by hordes of burglars. They can only be killed by luring or pushing them into your garden’s traps. Choose one of the 4 weapon modes, and make them taste theft lure, or should we say failure!

Saucers is a rogue-lite top-down twin-stick arena style shooter featuring extensive weaponry and upgrade paths so that every run is unique. The further you get, the more weaponry you can stack up to devastating effect. THIS GAME REQUIRES A TWIN STICK GAME CONTROLLER TO PLAY.

Fast Food Wars is a bullet-hell shoot'em up rogue-lite game in a procedural generated restaurant with random power ups, weapons. You play as a burger fighting to claim back all the invaded burger restaurant from other fast foods

Survivor of the Journey is a survival game with rogue-like elements Survive in countless fantasy monsters Grow faster than the enemy that comes and knock them down Survive to the end and defeat the boss. Failed? Use your stuff to be strong. Can't you? Let's try our luck this time.

A roguelike wave survival game where greed is your greatest weapon—and your deadliest risk. Fight as 8 unique heroes, upgrade weapons infinitely, and choose from 30 perks with powerful benefits and painful drawbacks. How far will your greed take you?

Battle time and terror in a shoot & survive extraction roguelite. Select your hero and survive the relentless cosmic surge. Shoot, level up, topple bosses, and amplify your powers to cosmic levels. Embrace the Blastard within and unlock new heroes, powers, and perks to use on future runs.

🍩🔥🤪 Madness meets donuts! Smash Dough Mixers, outgun wild foes, and brave endless mazes in a roguelite rampage!

Stranded in Starlight is a top-down roguelite where you pilot a spaceship armed with a variety of unique weapons and utilities. Battle relentless enemy hordes and powerful bosses as you upgrade your ship, adapting to each challenge in an ever-changing fight for survival.

Face endless waves of enemies through diverse builds and weapons, and uncover the promise that drives Newton to rise through the skies in this Roguelite Side-Scroller.

"Epsilon Zero" is a fast-paced top-down action roguelike shooter where every mission is an all-out assault. Use devastating weapon combinations, unlock powerful upgrades, adapt your tactics, and exterminate everything standing in your way.