Top similar games like Genesis: Rise of Life:

Clone yourself to take over the environment in this bacterial evolution roguelite. Choose mutations and abilities each time you multiply. Use swarm mode to direct your species to attack enemies. Unlock abilities and perks to improve your odds. Compete against other multiplying and evolving species.

The Animal Evolution Roguelite. Hunt, Flee, Scavenge and Thrive in a living ecosystem. Choose from 125+ Evolutions and Specialisations for unique creature combinations in every run. Adapt to survive the natural curve in order to beat carcinisation... or get Darwin'd trying!

Explore, mine, and fight your way through the galaxy in this 2D space mining adventure! Unearth the relics of ancient civilizations and face the horrors that linger beneath alien worlds.

Starcore Survivor is a top-down arena auto-shooter roguelite. Move, dodge, collect materials, and shape each run through 20 waves of combat, upgrade choices, between-wave shops, weapon fusion, evolution recipes, relics, bosses, and escalating Danger levels.

Salvo Shuffle is a bullet-hell roguelike that mixes turn-based and action-based combat.

Run. Fight. Eat. Repeat. In this creature evolution roguelite. Hunt with 100+ abilities and run-altering relics, pick your element and exploit theirs, every boss you beat evolves your body. Twenty minutes, one life, a different creature every run!

WE ARE REBELLION is a strategy and simulation game in which you command a warship with a crew of rebels. The game is set in the distant future, in a world that has been ravaged and polluted by capitalist corporations.

In this survival roguelite, you must survive a consistently changing 3x3 grid of different biomes, resources, animals, enemies, and more! Build structures and traps to protect a magical totem that heals you and provides upgrades to your weapons and gear. Every day, the world gets more dangerous!

Primordialis is a physics-based roguelike fish builder. Unleash your creativity to defeat creatures using venomous tentacles, electrical shocks, or exploding children. The possibilities are endless. Explore the primordial depths to reveal its secrets and discover what lies beyond.

Survive as a legendary dinosaur in a dynamic world! Traverse deadly biomes, avoid fatal hazards, and make split-second decisions before the cataclysm changes everything

Go down. Get stronger. Come back alive. Mine the mountain. Defend your shuttle. Adapt or get overrun.

In this 4-player co-op survival craft game, you and your friends are trapped inside a cursed, ever-changing board game. As members of the Mystery Club, you must uncover the secrets of Cryptfall, craft powerful tools, and defeat terrifying Cryptids to escape—before the island consumes you!

Purification Frontline is a post-apocalyptic roguelite bullet-hell action shooter. Build your squad, switch characters in battle, collect relics, and carve your way through branching tower runs with fast-paced combat and explosive firepower.

A survival roguelike where a frog digs through freezing snow, uncovers treasures, unlocks upgrades, and battles mystical creatures. Find the escape door — or defeat the final boss to survive.

The game combines action roguelike mechanics, platforming, village building, puzzles, and combat in a procedural world where you never know what might happen. You must fulfill the demands of a mysterious god or you will be destroyed!

It’s a forest at night, and the hunt begins. Carefully plan your pack’s next move to avoid being seen, smelled or heard. Hunt enough prey to survive the next month, and develop your pack and tactics throughout changing seasons. You’ll fail – but learn from your mistakes and prepare for the next run!

You are a blob. A small one. Eat everything smaller than you, get bigger, eat the things that used to eat you, and mutate your way out of the petri dish one strain at a time. Somebody has clearly lost control of this experiment. Good.

A New Kind of Action Game Where You “Get Weaker” the More You Play. Words wage war. Every enemy, every weapon, and you yourself — everything is made of words. Cut through hordes of living characters, seize skills, and evolve from Human to God.

Confront various terrains as a lonely mountaineer and endure the countless dangers of climbing! Many tough decisions await you in a risky environment. Make your way up and down the mountain, overcoming insurmountable heights!

Swallow swarms of monsters, earn XP, improve your stats, repeat. Minimalist active incremental roguelite with rewarding and satisfying gameplay. Reincarnate to get permanent XP bonuses and to unlock perks and Epic Bosses. Play alone or with friends.

Pick up and smash bugs, upgrade your tools to protect your potato patch from escalating waves of pests!

Sipho is an action survival game with an intricate building system. Grow your own creature and take over the local ecosystem. Fight, grow, survive, dominate. Play in adventure or sandbox mode.

A tactical defense game where you build the battlefield itself. Lure enemies through your maze using traps, towers, and godly powers.

An Amoeba with a gun blasts through countless waves of strange microorganisms in this unique top-down roguelite shooter. Find crazy items, create powerful builds, and survive as long as you can.

This game adds rich props and random elements on the basis of mine sweeping. You will play the role of an explorer collecting treasures on more than ten islands and constantly improving your abilities during the adventure, experiencing a journey of hidden dangers and rebirth.

BARREN is a road-trip immersive sim featuring realistic weapon simulation that takes place in a vast cold and nostalgic desert.

Desmarchon is a chain-weaving survivor-like. Burst drifting Anomalies, build your ship through sixteen Campaign operations, then farm thirty Deep Space destinations. Craft gear, insert Reality Manifolds, and push a shared Depth frontier as far as your build can carry you.

Play as Cyrus, a medieval knight, in this top-down action roguelike. Battle your way through endless procedurally generated dungeons filled with coins and weapons. Discover rare, powerful modifiers and test your skills against a variety of deadly foes.

Build settlements, command the Echoes of former lives, and race against a corruption consuming the world. Echo Harvest is a colony roguelite where every failed timeline becomes part of the history that shapes the next.

Defend a mad garden in this top-down action roguelite. Face waves of mutant pests, collect seeds, fuse weapons, choose powerful upgrades and grow each vegetable hero through permanent progression. Build your arsenal and survive the final wave.

One wrong jump ends the mission. Explore 76 real worlds, from Mercury to TRAPPIST-1e, built from NASA data and astronomical research. Manage scarce resources, survey distant worlds, and search for humanity's new home in a science-driven space roguelite where every run could be your last.

One More Tower is a horde survival TD set in a medieval fantasy world. Pioneer an unexplored forest, build your town and defenses, and hold out against the onslaught of enemies. How long can you survive?

Combine chemicals, prepare potions, and battle hordes of mythical monsters in this action-packed, chemistry-themed roguelike. You'll fight your way through a procedurally-generated science lab, exploding endless enemies and solving various puzzles, all to earn coins and upgrade your equipment.

Dragon Tiles is a lightweight top-down action roguelite bullet-hell survival game. Lead a chain of multiple heroes in a snake-like formation, automatically attacking and clearing waves of enemies while upgrading your team through the shop after each round.

In this top-down roguelike shooter game you go through levels of enemies to defeat [???] which escaped from [???]. You do this with the help of weapons and items you find on the way. You can equip up to two weapons. Mix and match the weapons and items you find to make combos that work together!

Become a Captain! Fly your ship and command your crew as you compete to become Champion in a winner-takes-all reality show. Build relationships and plot betrayals to avoid getting voted off the season and become the last captain standing. Optional VR support.