Top similar games like Doc, I Don't Want to Die! Slice the Infection:

An Amoeba with a gun blasts through countless waves of strange microorganisms in this unique top-down roguelite shooter. Find crazy items, create powerful builds, and survive as long as you can.

An interdimensional rift just ruined Mothman's peaceful shack life! Into the Lumberwoods is a fast-paced top-down bullet hell roguelite about a very annoyed Mothman defending his woods using anything that isn't nailed down. Venture into the woods and blast weird monsters back to where they belong.

Defend your Lifenode from waves of Scrollers, Trolls, and Doomscrollers in this chaotic 2D arena shooter. Upgrade, survive, and beat the algorithm.

Retro-style sci-fi top-down shooter and strategy game.

Dead End Job sends you into a madcap, Ren & Stimpy-esque world to bust up ghosts. It’s a procedurally generated, couch co-op, twin-stick shooter that straps a vacuum pack to your back and puts a plasma blaster in your hand. For you, it’s just another day in the office.

PLUMBUM is a retro top-down roguelike shooter where you'll have to survive the innumerable hordes of mooks and goons in the cursed corridors of this cursed game. Will you survive as long as you can, or will you die trying?

Spent Shells is a high score top-down shooter with roguelike-y randomized elements. Players dive in to an everchanging dungeon to harvest a crystalized power source that will get them home. Fight through the dungeon using a variety of weapons, characters, upgrades, and your own skill! Each run ea...

Fast Food Wars is a bullet-hell shoot'em up rogue-lite game in a procedural generated restaurant with random power ups, weapons. You play as a burger fighting to claim back all the invaded burger restaurant from other fast foods

Overkill Squad is a ultra high-speed top-down shooter roguelike built around intense 1-minute combat arenas. Choose your fighter, unleash overwhelming firepower, defeat brutal bosses, and collect relics to dominate every run.

Danger Gazers is a post-apocalyptic roguelite top-down shooter where you pave your own path. The choices you make will decide your fate, it will either turn you into the new ruler or... the ashes to be windswept away.

Core Breach is a fast-paced, twin-stick arcade shooter in a pixel art style. Play as a Trojan worm virus, outmaneuvering and destroying antivirus enemies. Upgrade your worm with powerful attacks and skills as you fight to breach the CPU core and uncover its secrets

Dodge, shoot, survive! Polygon pursuit is an arcade-style twin stick shooter where you are pursued by multiple enemies constantly. You play as a lone circle confined in a polygonal world fighting to survive against waves of unique enemies. This is not an easy game.

A broke bounty hunter. A sarcastic robot. 1,000,000 credit debt. Star Scrap is a chaotic twin stick space roguelite. Blast through increasingly difficult waves of enemies to pay it off.

You are an invincible bodyguard. Your only weakness is the person you must protect. Control the crowd, spot the assassin, and execute the mission in this stylish, top-down tactical shooter.

AGIS - A Game In Space is a top-down twin-stick-shooter.

C6: Frontlines is a bullet hell co-op roguelike where only YOU (and your friends) can bring the Azapall galaxy to peace. Wield 30+ weapons and gadgets of mass destruction to even the playing field, wave after wave, against a seemingly endless onslaught of evil!

Shapes & Shots is a Roguelite Shooter Bullet-hell, where you can control time as you make your way through a twisted and delusional universe. Your enemies will merge, creating infinite combinations to try to overwhelm you: only your skills, combined with upgrades you choose, can lead you to victory.

Explore dungeons, battle hordes of monsters, and defy fate in “Enter The Lost Chamber,” an action-packed pixel art roguelike. Discover new challenges, collect powerful weapons, and prepare to face the final boss at any time. Dive into the darkness!

Lumbrix is a survivors-like shooter where every segment of your growing worm is both a weapon and a life. Aim your head cannon, shield yourself with your body, evolve your weapons and survive ten minutes to face the boss.

An action rogue-like about garden plants fighting back against the hungry pests that threaten their home. Spend the day blasting through hedges to find loot, but take care to make it back before dark! Gather synergistic items, confront formidable bosses, and play as several unique characters!

A Mystic Gate created by the gods suddenly appears in the human world. Adventurers challenge themselves with the tests that await them beyond the gate. In order to earn your wish you must defeat hordes & bosses in this roguelike dungeon exploration bullet hell!!

Locus Protocol is an incremental rogue-lite retro styled twin stick shooter with heavy sci-fi and horror themes. Protect the core from waves of incoming enemies.

Gun Garden is a dungeon crawler top-down shooter with roguelike elements. Explore rooms, find gear, fight enemies, and level up your stats as you progress through the various floors, attempting to find what lies at the end of the Gun Garden.

Gospel of Abaddon is a 2D mix of RPG, Shooter and Roguelike. During WW2, an American pastor deserts the army and after using amphetamine, he sees God telling him to destroy the entire sinful world...

TV Boy is an action packed top-down shooter. Blast waves of weird and whacky enemies with even weirder weapons to rescue the captured citizens of TV Topia and restore peace to the galaxy!

Dive into a fast-paced underwater roguelike! Battle swarms of sea creatures, cursed pirates, and colossal bosses as you explore unique aquatic biomes. Collect a variety of weapons, uncover treasures, and survive the unknown in an epic journey through the ocean depths!

Cellosseum is a bullet heaven following the progress of a lone cell as it battles a variety of enemies on its quest to guide the evolutionary process of life itself. Upgrade your attacks, shields, health, and speed to understand your role in the creation of life on the planet of Ceres Prime.

Negative Time is a top-down shooter with bullet hell and roguelike elements where each time you get hit, you are sent further and further back in time, until you are sent into the past they tried so hard to erase. Maybe in there lies the key to your escape?

A roguelite where superstitions take shape as items! Face enemies, collect drops with negative effects that can be traded for advantages. Explore always different rooms, with challenges inspired by beliefs that make us think twice before taking a risk.

Go back and forth in a hail of bullets , use all kinds of weapons to take down your enemies.

Collect synergizing items to create an overpowered character to fight hordes of cyclops monsters. Cyclo Chambers is a fast-paced, top-down arena shooter with light rogue-like elements. 150 items to choose from to create frantic combinations. Different runs every time.

Shapes & Shots is a Roguelite Shooter Bullet-hell, where you can control time as you make your way through a twisted and delusional universe. Your enemies will merge, creating infinite combinations to try to overwhelm you: only your skills, combined with upgrades you choose, can lead you to victory.

cursor+cursor is a fast-paced arena shooter where you don't control one avatar... but two at the same time! Position your pair of cursors wisely to protect your core, upgrade your equipment and create unique builds to survive, all the while enjoying a "minimalist cyberpunk-ish" vibe.

Huedini is a colour-matching action roguelike game. Play as Huedini, a powerful wizard with the ability to change his colour. By matching your colour, to that of the enemies you can absorb their colour essence. By combining these colour essences into the correct combination, you can cast spells.

Exosoul is an adrenaline-fueled top-down shooter that will test your skills and reflexes. Fight for your life against relentless enemies while trying to synchronize your body and soul. You have a powerful arsenal of weapons at your disposal, but you'll need to use them wisely if you want to survive.