Top similar games like Guts and Syringes:

Rocked by an explosive soundtrack, choose your band, place your equipments and defend the Rock 'N' Roll from everyone and everything who try to pull it down, on a totally hardcore tower defense!

Defense Grid: The Awakening is a unique spin on tower defense gameplay that will appeal to players of all skill levels. A horde of enemies is invading, and it's up to the player to stop them by strategically building fortification towers around their base.

Fight off hordes of monstrous mutants created from a strange cataclysmic event in the new tower defense game, Prime World: Defenders. Join a group of exile treasure hunters who have ventured into the capital of an ancient empire, vast with mystery and danger.

Slice them, burn them, skewer them, and launch them - no matter how you get it done, orcs must die in this fantasy action-strategy game from Robot Entertainment.

Do you like Tower Defense games with Strategy elements? Well, look no further! We've got exactly what you're looking for! Get ready to defend your settlement from enemies using a huge arsenal of towers!

Defend your garden from a bug invasion using everyday objects turned into turrets: magnifying glasses, garden hoses, UV lamps, and more. Upgrade your defenses, adapt to changing weather, and outsmart increasingly cunning enemies in this strategic tower defense with a backyard twist.

Night Spasm is a meta-narrative open-world adventure game that adapts to your real-life philosophies and worldviews. From the characters you befriend to the quests you take, the game tracks and remembers your every move to create an adventure-... you're NOT a part of??

You think Tower Defense games are all about building? You thought wrong. Sanctum is not your average Tower Defense title. When the havoc starts, you get to join the fray! As one of the world’s first First Person Shooter - Tower Defense games, Sanctum has taken the best of both worlds to deliver an epic, one-of-a-kind experience.

A hybrid card game and tower defence where the hands you play become the towers you build. Defeat the enemies approaching the bear's den and find modifiers that support the elements of your defensive strategy.

Battle friends over air, land and sea in this epic WW2-themed battle strategy game.

What if MOBAs and RTS games had a baby? Rover Wars combines resource management, farming, building and strategy into an intense tug of war. Fight in an interplanetary campaign and challenge your friends in the configurable Battle Mode. Rover Wars might be your gateway ticket into the strategy genre.

While a formidable evil emerges, an unexpected alliance is taking shape! It will take the finest warriors of Linirea and the relentless Dark Army to stop it. Beware! Though they may journey side by side the ever-changing winds of fate could swiftly alter their course.

The Rift is a tower defense game with elements of RPG gameplay that will appeal to players of all skill levels. Enemies from an alternate universe are attacking and it's up to the player to stop them by strategically building defensive towers.

Dungeon Defenders Eternity is the definitive version of the original tower defense action-RPG! Now featuring a rebalanced endgame, all new missions, secure online play, links to Dungeon Defenders II and more!

Explore dark caves, mine valuable resources, and build defenses to survive waves of creatures. Caveward combines action, mining, exploration, and tower defense in a 2D pixel art adventure.

你需要在 9 天的时间内找到这个星球上的一处安全地。你的飞船燃料不足，必须降落。为飞船收集更多燃料的时候，在你周围设置哨兵枪以保护自己。由 人工智能操纵的“无人机”和“坦克”会攻击你，试图找出你防御系统中的弱点。

An epic, challenging tower defense game with an emphasis on strategy and replayability. Summon gems of immense magical potency and harness their unique abilities against a seemingly endless horde of monsters. The archdemon seeks to swallow the world, and you must journey to stand against her.

Lead the Stone Elementals in a fight for survival. Build and grow a thriving city, gather resources, craft powerful equipment, and prepare your warriors for challenging nightly battles as you defend your civilization in a hostile world.

Go head to head with other players in a Bloon-popping battle for victory. From the creators of best-selling Bloons TD 6, this all new Battles game is specially designed for multiplayer combat, featuring the ability to control bloons directly and send them charging past your opponent's defenses.

Take the journey of the Portal Protector as you defend the portals to the divine realm from evil. Use strategy and skill to aid you in your defense against evil using magic, sword skills, and defensive towers. For you are the Portal Protector!

Brace for enemies, prepare for mania. Hordes monstrous enemies are after your treasure! The only thing that keeps them away is your arsenal of weaponry: cannons, catapults and bombs. Arrange your weapons carefully and defeat the enemies before they reach your treasure.

Get ready for an epic journey to defend your kingdom against hordes of orcs, trolls, evil wizards and other nasty fiends using a vast arsenal of towers and spells at your command!Fight on forests, mountains and wastelands, customizing your defensive strategy with different tower upgrades and specializations!

Space Run is a «real-time spaceship construction strategy game». Space Run takes the well-known Tower Defense-style gameplay and twists it, challenging you to manage and protect a spaceship and its cargo against the hazards of deep space!