Top similar games like Genetic Disaster:

Rampage Knights is a cooperative beat 'em up game mixed up with randomized dungeon crawling and exploration, which you can play alone or with a friend online.

NECROPOLIS: BRUTAL EDITION is a major update featuring a new playable adventurer (The Brute), a completely new outdoor environment (The Black Forest), and lots of new enemies, weapons, armor, traps, potions, scrolls, and other big improvements to the game.

Fallen heroes of old folk tales and legends: you are on the verge of a crucial battle against the Nightmare invading and corrupting your world. A roguelike action game from the creators of Curse of the Dead Gods©, playable solo or in online co-op.

Black Future ’88 is a Synth-Punk roguelike 2D action Shooter. Vertically climb an always evolving procedural tower to reach the top and kill its insane owner…before your heart explodes. Shoot, slash, dash and upgrade yourself to survive the endless waves of Homicidal AI, Traps & Colossal Wardens.

Ship of Fools is a seafaring cooperative roguelite. Set sail, man the cannons and battle sea monsters through the tempestuous seas of the Archipelago. Are you fool enough to stop the Aquapocalypse?

Risk of Rain is an action platformer with roguelike elements. With permanent death as a primary feature, players will have to play their best to get as far as possible. Fight on a mysterious planet with randomly spawning enemies and bosses, either alone or with 3 friends in online co-op.

A roguelike game where you use abilities & items based on child logic to help Billy fight his nightmare. Poison bullies with a pair of Stinky Socks, set creepy toys on fire with a Magnifying Glass or make them step on some painful Pego Bricks!

CHRONAC! The roguelike action game where you shoot, slash, blast your way out the facility that created you. Gain powerful upgrades, face unforgiving enemies. Together.

Shoot aliens, fly around and make everything explode, alone and with friends, in this frenetic 2D run and gun roguelite. Survive the procedurally generated environment, collect weapons, level up and defeat planetary bosses. Improve between runs and discover new planets as you win.

Spelunky is a unique platformer with randomized levels that offer a challenging new experience each time you play. Journey deep underground and explore fantastic places filled with all manner of monsters, traps, and treasure.

Use guns to combine elements in surprising ways to unleash powerful reactions. Loot artifacts and guns to build the most unique and godlike builds. Go solo or with your friends up to 4 players.

Suit up, grab your guns, and embark on a cosmic heist in this fast-paced bullet-hell roguelite. Solo or with friends, your goal is to overcome enemy packed dungeons and steal the Solar Core. Raid, loot, unlock powerful skills, create unstoppable builds and prepare to die.

Bard's Fault - A cooperative multiplayer roguelike where every death makes you stronger. Survive against waves of enemies and uncover the mysteries of your destiny.

Battle through shifting roguelike dungeons in this up to 4‑player co‑op RPG, wielding elemental magic and outsmarting a dynamic Dungeon Master.

Woodpunk is an exhilarating roguelike bullet hell retro pixel art shooter in a medieval Woodpunk universe, where the primary energy resource is WOOD.

Escape a chaotic alien planet by fighting through hordes of frenzied monsters – with your friends, or on your own. Combine loot in surprising ways and master each character until you become the havoc you feared upon your first crash landing.

Take up arms and take care of robot buddies in this co-op action roguelite. Hunt giant hostile robots that have stolen the sun to harvest their mechanical parts, upgrade the machinery you can build and strengthen the bond between you and your Nova robot buddies!

Now reimagined and expanded in the new Mormo's Curse update, The Swords of Ditto is a roguelite action RPG that creates a unique adventure for each new hero of legend in the relentless fight against the evil Mormo.

Gunfire Reborn is a level-based adventure game featuring FPS, Roguelite and RPG. Players can control heroes with various abilities to experience diverse Build gameplay, use various weapons to explore procedurally-generated levels. You can play the game alone, or join 4-player coop.

Embark on an epic journey in this hardcore Multiplayer RPG! As a Galactic Cadet, you and your Combat Squad of friends must brave hostile worlds in search of valuable loot and resources. Craft powerful gear, slay otherworldly creatures, and save the galaxy.

Legend of Dungeon is a randomly generated action RPG Beat'em'up with heavy Rogue-like elements, striking visuals, and dynamic music.

Danger Gazers is a post-apocalyptic roguelite top-down shooter where you pave your own path. The choices you make will decide your fate, it will either turn you into the new ruler or... the ashes to be windswept away.

In this sequel to GoNNER: Journey your way through deep dark chaotic places with unimaginable sparks of colour as you go on a mission to help Death rid a mysterious presence from her lair. Battle crazy bosses, lose your head (a lot), in this messy, cute, fast-paced procedurally-generated platformer.

Challenge the tower solo or co-op in this high-octane sky crawler action rogue-lite. Stack power ups and steal destructive weapons as you dodge, dash and mutilate your way to the top. Your retribution awaits.

Paranautical Activity combines the classic FPS action of games like Doom and Quake, with the randomness and difficulty of modern roguelikes like Binding of Isaac and Spelunky.

Journey to the dark heart of the Edgewood Home for Lost Children in this fiendishly difficult action RPG!When her teacher stepped out of the classroom a month ago, Cordy never imagined he would be gone for good. Now her fellow students have turned on each other as the school descends into chaos.

Assemble a cyber agent team to infiltrate procedurally-generated bases in this co-op stealth roguelike adventure. Master highly tactical combat, a cache of cyber weaponry, and teamwork to save humanity from mind-control.

A 4-Player co-op shooter roguelite! Get together with up to 4 friends, defeat hordes of monsters, and upgrade your powers to survive in an anime-style wasteland.

Set sail in Crimson Cutlass, an epic rogue-lite pirate adventure! Battle foes, explore endless islands, and upgrade your ship in a world where mutiny could make you captain. Team up in local and online co-op via Steam Remote Play, uncover treasures, and conquer the Shifting Seas. Wishlist now!

From indie Chilean developer ACE Team comes a new side-scrolling action adventure game featuring a complex fighting engine in procedurally generated levels that destines its three warriors to battle a different abyss each time! Choose your hero and also learn to possess your enemies in the abyss…

Synthetic Paradox is a sci-fi action rogue-lite mixed with tower defense elements. Fight never-ending waves of enemies and bosses, collect items and build up your defenses alone or in co-op for up to 4 players! Discover unique combinations of towers and items to help you protect your Core!