Top similar games like Deck of Defense:

Tower defense meets deck building in Deck Defense. Defending against the blobs is no easy feat. Will you prioritise fortifying your tower defenses or expanding the map? Build your deck with over 75 cards to choose from.

"Plants vs. Animals" is a TD game where players, as plant summoners, collect and upgrade plant cards against animal waves. Victories yield new cards and genetic materials for card mutation and enhancement.Strategic card play and evolution are key

Combine tactics and strategy in this roguelike deckbuilder, where you must build your deck, train and evolve your team. Step into a mystical world where the Genkai battle in a quest for power and harmony, and prepare for the imminent arrival of the Primal Genkai.

Krumit's Tale, the second game in the Meteorfall universe, is a new take on the deckbuilding roguelike genre. Use your cards to clear dungeons, then upgrade your deck with new cards and perks to press forward. The fate of the world is in your hands.

Spliced is a hybrid roguelite deck-builder. Play as a symbiotic ooze, taking the parts and abilities of enemies you defeat. Use cards to battle enemies and navigate the environment.

In this turn-based roguelike deck-building game, you must recruit troops and use artifacts to repel the gnoll army until help arrives. Every new day the story unfolds, revealing new threats but also surprises. Roll the dice and command your troops to protect the kingdom!

Now fully rebuilt and remastered, Guild of Dungeoneering Ultimate Edition is a turn-based dungeon crawler with a twist: instead of controlling the hero you build the dungeon around them.

Dog Witch is a roguelike deckbuilder where your spells are fueled by enchanted dice. Combine over 150 unique items to forge ever-evolving strategies, perfect synergy combos, summon minions, and tackle an endless range of foes so bizarre, they’ll leave your tail wagging in disbelief!

A tactical roguelike deckbuilder where every move matters. Master a tight 6x6 grid, chain lethal card combos for massive gold rewards, and climb the Ascensions to face The Master. In this arena, positioning is power.

Balatro Meets Blackjack with a Cuphead aesthetic in this casino rogue-lite where you gamble with you abilities. Every chip you bet can turn the tide in your favor, but you could also lose it all in a bad hand. Think you can beat the house? 

Choppy Waters is a quirky, sushi-themed roguelite deckbuilder. Gather fresh ingredients, craft powerful sushi cards, and engage in turn-based tactical battles as you navigate a procedurally generated map. Discover clever synergies to outwit pirates, cultists, and all manner of monstrous foes!

Portal of Defense is a strategy Roguelike tower defense game. The game can complete all operations by simply dragging and dropping with the mouse. Explore the portal and obtain powerful items to become stronger and resist the tide of enemy attacks.

A whimsical roguelike deckbuilder with rich card interactions and deep synergies. Strategize through perilous space missions by assembling powerful crewmates and gadgets. Can you beat your objectives before time runs out?

We fused card games and roguelikes together to make the best single player deckbuilder we could. Craft a unique deck, encounter bizarre creatures, discover relics of immense power, and Slay the Spire!

Enter a papercraft world in this single-player, deck-building, card-battling, roguelike strategy game. Use your wits to battle your way through waves of enemies, while rewriting the very definitions of the cards you hold.

Party Demon is a tower defense, deck-building game where your main goal is to protect a Lady Demon’s birthday party from human intruders. Build your castle on a budget and defend it in real-time with a deadly Trap Deck full of demonic weapons.

Tower Knight is a deck-building & tower defense strategy game. Build your deck to strengthen your position, level up your knight, and win by capturing enemy towers.

A Pachinko Roguelite where you shoot musical balls at problem-shaped enemies that won’t let musician monks meditate. Collect relics and scenario pieces, build synergies, and place them to construct the battlefield itself.

Build twisting mazes with tetromino blocks and deploy unique towers in this strategic roguelite tower defense adventure!

Tower Deckfense is an exciting blend of tower defense and deck building. Build your deck strategically, upgrade your towers, and equip them with powerful modifiers to discover the best combinations and devastate your enemies.

Carefully craft your Mosaic in this fantasy themed deckbuilding game. Battle by battle, tile by tile, you'll form synergies and build up your Mosaic's combo potential, hoping to beat the curve as you forge deeper into enemy territory.

The fusion of deck-building roguelike and tower defense returns, bigger than ever! Build your deck with powerful new cards, unlock unique trinkets, and deploy enhanced towers to overcome relentless waves of enemies and new strategic challenges.

A tactical deckbuilding game where you fight enemies, unlock cards, and build your deck before each battle—discard cards to generate energy and control the flow of every fight.

A roguelite deckbuilding adventure game about magical coins. You play as a lootmancer, who can unlock the hidden power inside of coins and use them in magical duels. The loots you take from chests and enemies also become your next moves, so plan carefully!

TEKO is an Indie Roguelike Deckbuilder where you have to reach the highest possible score by playing Poker hands, but in an unconventional way: making 3 combos at once.

This is a deck-building card game that blends a 3×3 board, sacrifice summoning, and "3-point alignment" mechanics. As a challenger, you arrive in Diamond Town, a place gathering master card duelists. Here you will grow, battle formidable opponents, and aim to reach the top of Diamond Town!

Grid management roguelike tower defense that emphasizes mechanics and features dazzling visual effects. Don't overthink it, just stack and play! Enhancement modules boost your attributes, affix modules change the mechanics, and more... all within the grid. Time to create a new and improved build!

We fused deck-building roguelikes and tower defenses in a way never seen before - deploy your towers, collect valuable trinkets and cast powerful spells to defend yourself against the Salkoth!

A hardcore auto battle rogue-like deck-building (H.A.R.D) game, "Corrupted" has the strategy of an auto-battler and the challenging difficulty of a rogue-like. Build your own team and skill card deck, and retake the stolen planet through strategic placement and real-time card use!

Hexistence is a Tower Defense Roguelike Deckbuilder. Expand a procedural map, build towers, and cast spells while managing your hand in real time. Optimize your resources to survive increasingly demanding waves!

Deck Hunter is a roguelike card game. The World of Klanojh has been cursed by Glatta, the Goddess of Anger. Build your deck, make combos, defeat fantasy creatures and help Avery to face the evil and restore the balance!

A roguelike deckbuilder with a delicious twist. Think like a master chef, balancing resources as you strategically combo ingredients to subdue hungry hordes. Recruit a legendary kitchen crew, and rise through the heroic cooking guilds—before The Hunger consumes us all!

Build the ultimate Zoo in this number-go-up roguelike deckbuilder. Find powerful mythical animals, boost them with snacks, and even manipulate the board itself. Break the game by scoring millions (and more) with insane combos.

A roguelike memory deckbuilder where you bend the rules of card matching with wild combos, strategy-defining items and cards featuring some personality-packed cats.

Hurl emojis and battle the internet's biggest stars to rise as a meme master in Meme Mayhem! Collect powerful perks and relics, enjoy a darkly comic social media story, and assemble the ultimate emoji attack stack in this roguelite idle RPG.

Take on the ultimate tower defense challenge in Digs, a roguelike game where you shape the battlefield, mine resources, and strategize against a variety of enemies. Manage your actions, customize your arsenal with upgrade cards, and explore diverse levels. Can you dig in and emerge victorious?