Top similar games like Deck of Defense:

Tower defense meets deck building in Deck Defense. Defending against the blobs is no easy feat. Will you prioritise fortifying your tower defenses or expanding the map? Build your deck with over 75 cards to choose from.

We took tower defense and turned it on its head! Welcome to Rogue Maze, a Maze Defense game where the tiles are the towers. Plan out your maze, place directional tiles, add a few distractions, and watch as your underlings collapse from exhaustion.

"Plants vs. Animals" is a TD game where players, as plant summoners, collect and upgrade plant cards against animal waves. Victories yield new cards and genetic materials for card mutation and enhancement.Strategic card play and evolution are key

Combine tactics and strategy in this roguelike deckbuilder, where you must build your deck, train and evolve your team. Step into a mystical world where the Genkai battle in a quest for power and harmony, and prepare for the imminent arrival of the Primal Genkai.

Build mazes, customize your deck and travel through time, in a nostalgic tower defense game with a minimalist feel and a rogue-lite twist. Only you can save the Tree of Life from the malevolent forces of The Corruption...

Krumit's Tale, the second game in the Meteorfall universe, is a new take on the deckbuilding roguelike genre. Use your cards to clear dungeons, then upgrade your deck with new cards and perks to press forward. The fate of the world is in your hands.

Spliced is a hybrid roguelite deck-builder. Play as a symbiotic ooze, taking the parts and abilities of enemies you defeat. Use cards to battle enemies and navigate the environment.

In this turn-based roguelike deck-building game, you must recruit troops and use artifacts to repel the gnoll army until help arrives. Every new day the story unfolds, revealing new threats but also surprises. Roll the dice and command your troops to protect the kingdom!

Now fully rebuilt and remastered, Guild of Dungeoneering Ultimate Edition is a turn-based dungeon crawler with a twist: instead of controlling the hero you build the dungeon around them.

Dog Witch is a roguelike deckbuilder where your spells are fueled by enchanted dice. Combine over 150 unique items to forge ever-evolving strategies, perfect synergy combos, summon minions, and tackle an endless range of foes so bizarre, they’ll leave your tail wagging in disbelief!

Balatro Meets Blackjack with a Cuphead aesthetic in this casino rogue-lite where you gamble with you abilities. Every chip you bet can turn the tide in your favor, but you could also lose it all in a bad hand. Think you can beat the house? 

Choppy Waters is a quirky, sushi-themed roguelite deckbuilder. Gather fresh ingredients, craft powerful sushi cards, and engage in turn-based tactical battles as you navigate a procedurally generated map. Discover clever synergies to outwit pirates, cultists, and all manner of monstrous foes!

Card Conquest is a Tower Defense game with Deckbuilding and Roguelite elements. Combine spells, towers and units to create a deck and defeat your enemies. Spend your resources wisely and find balance between offense and defense. Gather powerful relics that will enhance your cards.

A tactical deckbuilding game where you fight enemies, unlock cards, and build your deck before each battle—discard cards to generate energy and control the flow of every fight.

Portal of Defense is a strategy Roguelike tower defense game. The game can complete all operations by simply dragging and dropping with the mouse. Explore the portal and obtain powerful items to become stronger and resist the tide of enemy attacks.

A whimsical roguelike deckbuilder with rich card interactions and deep synergies. Strategize through perilous space missions by assembling powerful crewmates and gadgets. Can you beat your objectives before time runs out?

We fused card games and roguelikes together to make the best single player deckbuilder we could. Craft a unique deck, encounter bizarre creatures, discover relics of immense power, and Slay the Spire!

Enter a papercraft world in this single-player, deck-building, card-battling, roguelike strategy game. Use your wits to battle your way through waves of enemies, while rewriting the very definitions of the cards you hold.

Party Demon is a tower defense, deck-building game where your main goal is to protect a Lady Demon’s birthday party from human intruders. Build your castle on a budget and defend it in real-time with a deadly Trap Deck full of demonic weapons.

Tower Knight is a deck-building & tower defense strategy game. Build your deck to strengthen your position, level up your knight, and win by capturing enemy towers.

Bills? Stress? Heartbreak? Find your inner peace in this roguelike deckbuilder where cute musical monks meditate atop mountain peaks. Each one plays a different instrument, and with the right mix of cards and relics you collect, you can use their music to banish your troubles.

Carefully craft your Mosaic in this fantasy themed deckbuilding game. Battle by battle, tile by tile, you'll form synergies and build up your Mosaic's combo potential, hoping to beat the curve as you forge deeper into enemy territory.

TEKO is an Indie Roguelike Deckbuilder where you have to reach the highest possible score by playing Poker hands, but in an unconventional way: making 3 combos at once.

"Zodiac Mountain" is a roguelike deckbuilder following the journey of a Panda as they adventure to become a Chinese Zodiac. Utilise dual hands of Yin & Yang, encounter fierce mythical characters, outskill your enemies in battle, and climb Zodiac Mountain.

The fusion of deck-building roguelike and tower defense returns, bigger than ever! Build your deck with powerful new cards, unlock unique trinkets, and deploy enhanced towers to overcome relentless waves of enemies and new strategic challenges.

A roguelite deckbuilding adventure game about magical coins. You play as a lootmancer, who can unlock the hidden power inside of coins and use them in magical duels. The loots you take from chests and enemies also become your next moves, so plan carefully!

Grid management roguelike tower defense that emphasizes mechanics and features dazzling visual effects. Don't overthink it, just stack and play! Enhancement modules boost your attributes, affix modules change the mechanics, and more... all within the grid. Time to create a new and improved build!

We fused deck-building roguelikes and tower defenses in a way never seen before - deploy your towers, collect valuable trinkets and cast powerful spells to defend yourself against the Salkoth!

A hardcore auto battle rogue-like deck-building (H.A.R.D) game, "Corrupted" has the strategy of an auto-battler and the challenging difficulty of a rogue-like. Build your own team and skill card deck, and retake the stolen planet through strategic placement and real-time card use!

A roguelike memory deckbuilder where you bend the rules of card matching with wild combos, strategy-defining items and cards featuring some personality-packed cats.

Hexistence is a Roguelike Tower Defense Deck Builder based on four universal elements: Matter, Energy, Space & Time. Place powerful towers and play wondrous spells to defend the Hexspire and restore the Ethereals coming from the Ether!

Deck Hunter is a roguelike card game. The World of Klanojh has been cursed by Glatta, the Goddess of Anger. Build your deck, make combos, defeat fantasy creatures and help Avery to face the evil and restore the balance!

Zoominoes is a roguelike deckbuilder. Play animal tiles, feed them powerup snacks, and boost them with souvenirs from the gift shop. Score massive points using crazy combos!

Hurl emojis and battle the internet's biggest stars to rise as a meme master in Meme Mayhem! Collect powerful perks and relics, enjoy a darkly comic social media story, and assemble the ultimate emoji attack stack in this roguelite idle RPG.

Take on the ultimate tower defense challenge in Digs, a roguelike game where you shape the battlefield, mine resources, and strategize against a variety of enemies. Manage your actions, customize your arsenal with upgrade cards, and explore diverse levels. Can you dig in and emerge victorious?

Cards of Prophecy combines Tower Defense, Deckbuilding, and Roguelike elements, with huge inspiration from Trading Card Games. Build an ever evolving deck to summon monsters and use powerful spells. Fuse, defend, open card packs, create new strategies. Repeat.