Top similar games like Mystic Resistance:

Crystal Guardians is a tower defense game with rogue-like elements. Fight of waves and defend the world crystal. Gear up your towers with a powerful combination of items for your strategy. In an ever expanding map, find hidden powers and conquer the enemies.

Dungeon of the ENDLESS™ is a Rogue-Like Dungeon-Defense game, in which the player and their team of heroes must protect the generator of their crashed ship while exploring an ever-expanding dungeon, all while facing waves of monsters and special events as they try to find their way out...

You are the guardian of a cursed labyrinth and must prevent an adventurer from escaping with the help of your monsters. But the adventurer keeps trying again and again, accumulating levels and getting stronger... Survive to the highest possible level !

Eyeb is an action packed tower defense-like that pits a young space cadet's bionic eyeball against a harrowing nano-bot invasion. Push out, explore, power up and drop a trillion towers for the glory of facing off with the diabolical Nano-Lord. You can also go fishing in space.

"Cluckmech Oasis" is a tower defense Roguelike with top-down shooting, players will play the battle chicken and its partners, in the journey to collect a variety of strange defensive machinery, a large number of plant enemies, along the way to escort base vehicles to save the world!

Tunnel of Doom is an action rogue-lite hybrid that mixes tower defense with melee and ranged combat gameplay. Randomly generated, every run is different as you guide Angel on a quest to rescue her husband. Gather resources, discover perks, and use what you find to battle waves of monsters.

Defend your castle, mine for minerals, and level up your wizarding powers in this thrilling action-roguelike game. Grab your wand and prepare to fight off magical foes in this epic battle for survival!

An auto-battler roguelite with tower defense and horde survival elements. Draft and position your army, develop your graveyard, equip units with powerful items, cast spells, and place turrets to annihilate your opponent's army in seconds!

Tower Defense mixed with Roguelike! Build overpowered Towers to beat masses of enemies. Unlock up to 5 different characters, more than 25 Towers and conquer epic boss battles to prove your strategic prowess in this endless battle for survival!

Snowbound is a roguelite farming game with tower defense elements. Build your farm, survive the night with a range of defenses, and complete missions to progress deeper into the forest.

Stellar Watch is a rotating tower defense roguelike where you can adjust turret defenses in real-time by steering them around enemy paths.

Tower Escape is a reverse tower defense game, where instead of defending against incoming enemies, you play the baddies and guide your minions to the exit. Recruit a team of minions, and collect powerful gems and relics that make each run unique.

Combination of roguelike and strategy in one side view game. Defend yourself against constantly attacking Elms while researching procedural research branches. Destroy the enemy or lose

A horde survival and tower defense mashup. Guard your traveling castle from an imperial army trying to hunt you down. Combine elemental bending styles and theorycraft the perfect set of game-breaking ability chains.

Defend your tower and protect the dwarf's treasure from marauding creatures in this roguelike tower defense game. Explore the region, collect resources and choose the right upgrades. But be careful, don't leave your fortress empty for too long.

Klondor is in grave danger of being overwhelmed, enter the Labyrinth, prepare your defences, defend your Mana Crystal and annihilate the incoming waves of enemy forces that pose a threat to the Kingdom.

"Slime Warfare" is a rogue tower defense game with a variety of gameplay and placement.Slimes are weak monsters and always bullied by humans. Players will play the role of the Slime Queen to build structures to defend against adventurers' attacks and strengthen themselves.

Role of Hex is a real-time strategy game where you defend your hexagonal base from the dangers of the universe. Gather upgrades and unlock special buildings to survive this hostile land as endless waves of enemies approach. But be quick, time is ticking and the waves are getting bigger.

TEOM is a roguelite strategy game that draws inspiration from the tower defense genre to innovate it through dynamic levels, interactive elements, and high replayability. Follow Aiden and his friends on an unexpected journey through this vibrant world.

Defend the evacuation of Terra on the losing side of an alien invasion. This experimental action strategy game breaks out of genre norms to provide fresh mechanics to strategic gaming.

Rogue Tower is a tower defense game with roguelike elements and a continuously expanding path which you can influence. Unlock, build, upgrade, expand, defend.

Try to survive in infinite asteroid cloud as long as possible in reworked tower defence style. FInd your own playstyle and beat your own records or chillout with original ambient soundtracks. Build, explore, think - everything to create your own colony in this cold space.

You wake up in a gloomy room where you are imprisoned. Only by mastering an enigmatic Tower Defense - Roguelike - Deckbuilder can you uncover the secrets lurking in the shadows of this facility.

A minimalist sci-fi tower defense. Buy soldiers and upgrade them, defeat waves of enemies, hold your lines.

Dungeon Rebound is the perfect blend of nostalgic arcade gameplay and immersive RPG elements, offering a fresh and exciting take on both genres. Are you ready to rebound your way to victory and become a legend in the realm of Dungeon Rebound?

Defend against waves of enemies with a strategic mix of spellcasting and tower defense. Explore new spells, towers, and artifacts in each run and discover your own playstyle in this rougelike Tower Defense game.

Terrorformer TD is a tower defense roguelite with a procedurally generated map that YOU shape! Raise or lower tiles, divert enemy paths and funnel monsters into perfectly designed killzones. Randomly drawn cards result in plenty of run variety, as you seek to survive endless waves of enemies.

Crystal Guardians prologue (small slice of the full game) is a tower defense game with rogue-like elements. Fight off waves and defend the base crystal. Gear up your towers with a powerful combination of items for your personal strategy. In a procedural map, find hidden powers and conquer the enemy.

Sentry System is a tower defense roguelike where you collect, modify and upgrade your sentries while progressing through a network of challenging encounters.

Hallway Defender is a roguelite tower defense where you defend your base from an endless wave of fellow classmates. With over 25 different towers and even more upgrades and effects there are infinite ways to set up your own defenses.

A rogue-like sci-fi Tower Defense strategy game with infinite replayability!

Tower Field is a roguelike tower defense game with a random generated world to explore and modular towers that you can customize and adapt to protect yourself from the dangers you discover.

packet.Breach() is a roguelike tower defense where you deploy hacker programs to manipulate and redirect projectiles to attack your enemies. Build your deck and join a hacker faction, or choose to remain unaffiliated and become a legend.

Isle of Arrows is a Puzzle Tower Defense game in which you build a fortress in the sky. Place towers, expand the isle, and build your own paths. Can you find the perfect spot for each tile to beat the RNG and defend against waves of invaders?