Top similar games like Infinium Strike:

Exo TD is a true 3D space Tower Defense. Invaders have scouted your planet as their next target, you must protect it by building destructive turrets, orbital defenses, shields, drones and more to defend against the incoming invasion force.

Immortal Defense is a story-driven tower defense game in which you give up your body and life to become an immortal "path defender", and defend your home world from destruction, forever. The game takes place over millions of years. Is there anything you would give up everything to defend?

Taur is an action-strategy sci-fi game. Control the Prime Cannon and unlock all of its powerful weapons and abilities. Build turrets, droids, aircraft and more as you fight to protect the homeworld of the Tauron droids against a relentless invasion. Will your Taur stand against the Imperion warmachine?

MILLIONS OF ALIENS WILL DIE!Radiant Defense is a tower defense game set in a vibrant universe invaded by countless alien hordes.Build your space fortress any way you wish, set up wide variety of weapons and traps and let the invasions begin!

You believed tower defense is only about building towers? That's not quite right – because AIRA VR is not like other tower defense games in virtual reality. Once the battle starts you find yourself in the midst of the fight!

Space Run is a «real-time spaceship construction strategy game». Space Run takes the well-known Tower Defense-style gameplay and twists it, challenging you to manage and protect a spaceship and its cargo against the hazards of deep space!

Dynamic online battles in real time with elements of strategy and cards game. Collect and improve cards of effects, turrets and intergalactic pirates: robots, aliens, monsters, insects and other extraterrestrial creatures.

Mine gold and electricity in your own space colony, find new inhabitants in space, and eventually make them happy - because the energy of happiness through smile-to-fly technology can be transformed into rocket fuel!

Join in on the next gold rush and become a prospector in space. In this unique tower defense you can set up and reposition towers for maximum efficiency and adapt to the environment.

Setting the bar as the definitive tower defense game, Defense Grid 2 introduces new worlds and threats to test your tower placement strategies. With a bold new look and the addition of new game modes, player-versus-player and multiplayer co-op, every play brings fun new opportunities and challenges.

Space Run Galaxy is the sequel to Space Run, the game from one-man studio Passtech, which seduced hundreds of thousands of players with its dynamic and original gameplay. By twisting the tower-defense game style, Space Run offered an addictive real-time spaceship construction strategy experience.

Sci-fi Tower Defense real-time strategy with pleasant adaptive music. Play as a commander of a space station which got stuck in a time anomaly.

Arc defence is a game in genre classic top down 2d tower defense, But in difference of classic TD, enemies can fight back. Use towers upgrades and special abilities to stop waves. Be ready for epic battle and try to protect our lands!

Get ready to rethink all your defense strategies! Build barricades to stop monsters, or lure them into a maze and attack. A variety of stages that change each time depending on how you play them.

Escape From The Red Planet simplifies resource management, tower defence, and first-person mechanics into a singular arcade experience. On the latest mission to Mars, the Orion III crash-landed. With Martian attacks looming, Houston most definitely has a problem!

Terminal squad: swarmites is a game with indirect control where you must erect a chain of buildings, which generate resources for construction or the combat units for destruction of an enemy.

Control two characters simultaneously! Survive, gather, collect upgrades, fight all sizes of one-eyed Martians, build defensible outposts and conquer Mars, in this glorious mix between roguelite and tower defense.

TEP the destroyer is a single player tower defense game where you will face alien monsters and ships in ground and space battles! Your strategy will decide the fate of your people in a sci-fi environment of varying difficulties!

Kind Heart Defenders is an experience that brings the best of Space Shooter with the best of Tower Defense. Have fun building towers, trying different ships, laughing at the characters' jokes, and battling through intergalactic scenarios and gigantic bosses.

Multiple levels, multiple weapons and enemies have their own characteristics, waiting for players to challenge.

Be the ultimate CEO and military strategist in this genre fusion of strategy and business management. Create your own company, hire employees, research weapon technology, and take control of units on the battlefield to defend the moon against an alien invasion. Aliens down, profits up!

Players measure stamina with a never-ending stream of green creatures within the borders of a special military mission.

Engineered to Purpose is a new tower defence game where you custom-design towers to defend your base, with millions of builds to explore and refine. Set in the far future, E2P's story of posthumanism, family, and change will open new worlds to explore and survive.

Space debris is out of control! Craft a station to take out the trash in this construction roguelite mashup.

Planetoid is a physics based building game in which you construct facilities and protect humanoids on the planetoid. Build a facilities which can defeat the enemies on your way.

A sci-fi roomscale VR Tower Defense game. Strategize to destroy waves of rogue robots and assist the powerful turrets with a handheld drone. Build and collect resources and help evacuate your crew from the alien planet.

AT THE LIMITS OF EARTH, AT THE EXTREMITY OF HEAVEN. A REAL-TIME STRATEGY NIGHTMARE.

Project Astra Dominium is a Tower Defense game with Basebuilding and Automation elements. Build up your base to become a supply hub for Earth's desperately needed materials, gather resources while defending against an unknown alien threat and improve your tower's and AI capabilities.

Build a space station. Command the tiny crew. Explore the galaxy. A meditative space strategy game.

Strategy, timing and fortune: Novel and immersive tower defense game experience!

Refactor is a hard-core tower defense game that combines modular building, route planning, and element composition.

Manage your very own space station in this Tycoon game. Sell fuel and repairs to the visitors. Manufacture and research new ways to defend your business and make more money while balancing your relations towards other factions. Survive against all odds.

A Third-Person Tower Defense game in which you are an Intern sucked through a portal who now must defend the objective from aliens.