List of the top Transhumanism games:

Caves of Qud is a science fantasy roguelike epic steeped in retrofuturism, deep simulation, and swathes of sentient plants. Come inhabit an exotic world and chisel through layers of thousand-year-old civilizations.

Picayune Dreams is a roguelike blend of bullet heaven horde survival, and bullet hell gameplay. Adrift across the endless void, you must fend off thousands of nightmarish and otherwordly creatures. Uncover a mysterious and surreal story. And don't forget. You mu [TRANSMISSION INTERRUPTED...]

Ein, a simple-hearted member of an expedition sent by mankind to distant planets, tries to get romantic with a pretty but cold co-worker girl. Unfortunately, he is not the only one trying to make contact as from the abandoned and desolate alien ruins, the girl receives a message in human language.

Set in futuristic Tokyo, take control of the robotic community before they control everything!

Immerse yourself in neon, smoke, and high-stakes legal gambles as a Defense Attorney with uniquely Killer insights in this episodic, diabolically stylish visual novel adventure game.

Lose yourself in the dystopian world of New York, 2329; immortality comes at a price that someone has to pay. In this interactive noir story, lead the investigation using advanced technology, as Detective James Karra who risks it all in pursuit of a serial killer targeting the city’s elite.

Embody the ultimate cybernetic corporate agent. Master deadly gunplay, time manipulation, and supernatural abilities. Hack computers, people, even the individual bullets flying at you. Confront the future, and die trying.

A visual novel about what it means to be human. A story about loneliness, self-identification, and the meaning of existence.

A massive-scale real-time strategy game where you command entire armies on a dynamic battlefield. Conquer multiple worlds across several single-player campaigns; or play with your friends in multiplayer combat.

The afterlife is now digital. Discover that eternal life comes with sacrifice in the first chapter of a genre-defying RPG with unique rhythm combat.

Arriving on a curious planet, Vix and her toolbox Tin explore space, fixing machines with unconventional tools and eating cozy meals with kind robot locals. On an epic adventure, the duo repairs an interstellar beacon, constructs giant mechs, and unravels a cosmic mystery that transcends existence.

A free game from the co-creator of Anodyne. Explore someone's mind and discover their secrets in this surreal, PSX-like adventure about a father, son, Asian-America and race. Control Yuito as you explore his dying father's "Memory World" - what supernatural things will you discover?

A beat'em up style action game, thrilling, hardcore. You can choose between exploring a cyberpunk city, takeover enemies' bodies; or perform a surgery for implants? You play as a female doctor with a mysterious past, hunting at night in Yayoi City and perform surgeries on day in her clinic.

Apex Heroines is a 3D light sci-fi action game that focuses on fast-paced and exhilarating battles, with multiple roles to choose from, beautiful fashions, and a variety of styles to create as you wish, so not only does it look great, but it's even better to play!

A corporate artificial intelligence simulator.

Experience deeply simulated, hex-based space combat as an elite starship pilot. Explore a ruined solar system, upgrade your ship, and lead your faction to greatness in this tactical, space RPG with 4X elements.

In the world of excessive biotechnologies, an epidemic is ravaging the human race, infecting people's neuronet implants and enslaving them to the mysterious Worm. Who are you: a fighter of the infection, or a hunter of new prey?

Traverse stunning pixel landscapes, collect resources, and solve genetic puzzles to bring life back to a desolate planet. Play as an android created by the last human in existence to retrace evolution and save the world from mass extinction, while discovering the true weight of the human condition.

Fast-paced vehicular shooter. Drive a secret vehicle on a mysterious icy planetoid in a remote star system to uncover what new and unusual threat is looming over the entire humanity.

Pilot a heavily armed Gravcycle in Disintegration, a new sci-fi first-person shooter unlike any other. Command your troops on the ground as you battle through a thrilling single-player campaign.

Sci-fi Visual Novel (Linear Story). A group of astronauts, scientists and robots is sent to space on a mission to investigate the disturbing disappearance of the first manned spaceship in its journey to Mars.

Join Ludovik in a 2D Stealth Platformer and Graphic Adventure, as he explores the jungles of a futuristic Babylon to discover the secret behind the Library of Babel’s sudden lockdown and the mysteries behind their mythical creators.

In this last city of mankind, an isolated paradise in the ocean, your choices and dices will lead it to Utopia or Distopia. You will help the magistrate AI to investigate the AI-worship religious group, illicit drugs, those who were resurrected, and those who are neither android nor mankind…

Our civilization has fallen. From the ashes, four new powers emerge. Immerse yourself in a combat-heavy twist on a classic turn-based 4X strategy where steam, steel, atom and diesel-punk corporations clash to spread their technology and the way of life.