Top similar games like Dr. Professor Scientist's Weapons Testing Facility:

Bestion is a game that combines Roguelike tower defense elements with automated factory construction. Players are required to construct their own factory on a planet and protect the kernel from monster attacks.

Be the ultimate CEO and military strategist in this genre fusion of strategy and business management. Create your own company, hire employees, research weapon technology, and take control of units on the battlefield to defend the moon against an alien invasion. Aliens down, profits up!

Axom: Conquest is a base building resource managing tower defense game set on the dangerous planet named Axom. Gather resources to build defenses, unlock research between games to get stronger and ultimately unlock the secrets of the mysterious planet.

TurretFall is a fast-paced roguelite tower defense game. Build and manage your base, collect powerful upgrades, grow your economy, and survive relentless waves of enemies and challenging bosses.

Towerbloom is a pathless roguelite tower defense with reactive gameplay. Employ countless outlandish strategies and supercharge your towers by hovering over them to vanquish enemies.

A Roguelike Tower Defense in space with missions to conquer. Can you hold against the spreading alien bosses? Build and upgrade towers against the corruption. Choose your technologies and warpspeed your way to victory.

SUPRACORE is a roguelike base building game. Build your base, upgrade it and defend against ongoing waves of enemies to gather more resources and expand your Core!

A rogue-like sci-fi Tower Defense strategy game with infinite replayability!

Refactor is a hard-core tower defense game that combines modular building, route planning, and element composition.

Blast through chaotic dungeons and unleash powerful weapons as you journey through the multiverse in search of a way home. Dodge, loot, and survive against deadly foes, extracting hard-won treasures to repair your ship and make it back!

Cosmic Stronghold is a mix of the genres RTS and Tower Defense. Your primary goal is to keep your space station alive for as long as possible, so that it can harvest the nearby mines for precious mineral ores. You will be faced with waves of enemies, getting stronger and stronger for each wave.

Stop an endless hoard of crystal-type enemies, with different attributes, from reaching the portal to earth! You can build your own labyrinths, unlock new turrets, upgrade them, unlock abilities, and also gather permanent bonuses.

Hostile Mars is a factory-building game focused on combat! Explore an open world and discover new tech to unlock powerful weapons and structures. Create efficient supply chains using delivery bots. Salvage destroyed enemies for resources. Design your base to withstand increasing waves of enemies!

Click to farm! Another Farm Roguelike Rebirth is a strategic farming roguelike where you craft, build, gather, and manage in order to earn money for the increasing rent. No boring walking or romance stuff; everything is done using a cursor!

Terrorformer TD is a tower defense roguelite with a procedurally generated map that YOU shape! Raise or lower tiles, divert enemy paths and funnel monsters into perfectly designed killzones. Randomly drawn cards result in plenty of run variety, as you seek to survive endless waves of enemies.

Defend attacks from enemies from all directions within a limited time. Only by making full use of the differences in each tower and choosing appropriate random rewards can you survive.

The Last Starship is a space-based construction, industry & factory game, currently in Alpha (expect regular free updates). Design star ships and take on a variety of missions from mining and passenger rescue to combat whilst working on the greatest engineering project ever attempted by humankind!

Co-op twin-stick base building survival game.

Evolve and fight in this creature building Roguelike. Grow a creature by attaching new cells, add mutations to create powerful synergies, fight real-time tactical battles against weird enemies, and strategically choose a path across multiple campaign acts. Inspired by games like Spore and FTL.

Tower Field is a roguelike tower defense game with a random generated world to explore and modular towers that you can customize and adapt to protect yourself from the dangers you discover.

In Lunar Loot you'll kill aliens to make money. In between waves of enemies, you'll spend that money to buy upgrades and items to make it easier to kill aliens and make money. You can't die, so just focus on getting rich!

Build & defend a small remote mining base on Taichin XI from the alien hordes. Deploy defenses, upgrade your turrets and get ready for the nightfall. The Unearthened is a classic Idle Tower Defense game where you build towers and prepare for the invasion.

Select unique spaceship models and multiple talents from 80+ options. Explore the world map, complete missions for gold, and shop for items. Defeat foes, earn experience, and enhance your spaceship's modules. Forge your style and prove its strength.

"miniBONG" is a lightweight rogue-like game that focuses on dress-up DIY and idle gameplay, while incorporating elements of combat, character development, and strategy.. You can feel the charm of dressing up and fighting at the same time.

Space debris is out of control! Craft a station to take out the trash in this construction roguelite mashup.

Corporate greed meets strategic planet-mining in Drill Core! Drill to the heart of planets while managing workers, researching cutting-edge tech, and fortifying against alien attacks. Will you prioritize efficiency and risk your workers' safety, or focus on defense for survival?

Eyeb is an action packed tower defense-like that pits a young space cadet's bionic eyeball against a harrowing nano-bot invasion. Push out, explore, power up and drop a trillion towers for the glory of facing off with the diabolical Nano-Lord. You can also go fishing in space.

Explore the mysterious Wall World on your giant robospider: mine for valuable resources, upgrade your equipment to fight off hordes of monsters, and discover exotic biomes in-between attacks. Will you be able to survive and learn the secrets of the Wall World?

Rionag: Survey Fleet is a top-down starship builder and logistics game where it's your job to balance the needs of the crews with cutting-edge equipment on board. Unlock tech that adds new capabilities for your ships to go through hazardous environments, enabling you to explore new worlds.

Grow your planetary empire from a small base to a massive production powerhouse in Planetary Factory. Balance inputs and outputs to maximize profits and minimize waste, research advanced technologies, and build a formidable military to conquer hostile planets.

A Simple Tower Defence Game. Build, Loot, Buy & Sell, Level Up, Quest... Controllable Difficulty, Custom Gameplay, Ingame Help.

A rogue-lite dice game in space! Build your ship as you explore randomly generated star systems, survive hostile encounters, and upgrade your colony ship for the next generation of chasers. Can you find a new home for your orphaned race amongst the stars?

Eversiege is a roguelike, tower defense in which you'll defend a castle in procedurally generated terrain. Establish a production, build defending buildings and survive waves of enemies coming from everywhere! After defeat, buy new buildings, unlock new leaders and prepare to fight again.

We fused deck-building roguelikes and tower defenses in a way never seen before - deploy your towers, collect valuable trinkets and cast powerful spells to defend yourself against the Salkoth!