Top similar games like Dr. Professor Scientist's Weapons Testing Facility:

Be the ultimate CEO and military strategist in this genre fusion of strategy and business management. Create your own company, hire employees, research weapon technology, and take control of units on the battlefield to defend the moon against an alien invasion. Aliens down, profits up!

Bestion is a game that combines Roguelike tower defense elements with automated factory construction. Players are required to construct their own factory on a planet and protect the kernel from monster attacks.

A rogue-like sci-fi Tower Defense strategy game with infinite replayability!

A Roguelike Tower Defense in space with missions to conquer. Can you hold against the spreading alien bosses? Build and upgrade towers against the corruption. Choose your technologies and warpspeed your way to victory.

Towerbloom is a pathless roguelite tower defense with reactive gameplay. Employ countless outlandish strategies and supercharge your towers by hovering over them to vanquish enemies.

Conquer the unconquerable. Drill for priceless resources while fending off an unrelenting alien force. Build, fortify and unlock devastating upgrades to become an unstoppable war machine as you uncover the planet’s darkest secret.

In Lunar Loot you'll kill aliens to make money. In between waves of enemies, you'll spend that money to buy upgrades and items to make it easier to kill aliens and make money. You can't die, so just focus on getting rich!

TurretFall is a fast-paced roguelite tower defense game. Build and manage your base, collect powerful upgrades, grow your economy, and survive relentless waves of enemies and challenging bosses.

One More Turret is an automation and tower defense strategy game with interesting innovations. Gather resources and enemy loot to construct intricate factory while defending against relentless monster waves. Can you strike the perfect balance between production and defense?

Survive on a hostile planet by automating a factory, fighting alien waves, and buying random upgrades. Hold out until the cleansing bomb drops! Roguelike strategy with drones & survival.

INTERGALACTICORP. is a sci-fi rogue-lite tower defense game where you take on the role of an operator-bot, charged with conducting an intergalactic mining operation. Will you thrive as an efficient miner in this alien environment, or succumb to the dangers that lurk in the depths of space?

Cosmic Stronghold is a mix of the genres RTS and Tower Defense. Your primary goal is to keep your space station alive for as long as possible, so that it can harvest the nearby mines for precious mineral ores. You will be faced with waves of enemies, getting stronger and stronger for each wave.

A Strategic Incremental Clicker, in which you should try to protect your city from waves of volcanic enemies. Gather resources, defend yourself strategically and upgrade your city to discover the secrets behind these attacks.

Stop an endless hoard of crystal-type enemies, with different attributes, from reaching the portal to earth! You can build your own labyrinths, unlock new turrets, upgrade them, unlock abilities, and also gather permanent bonuses.

Combine chemicals, prepare potions, and battle hordes of mythical monsters in this action-packed, chemistry-themed roguelike. You'll fight your way through a procedurally-generated science lab, exploding endless enemies and solving various puzzles, all to earn coins and upgrade your equipment.

In MegaFactory Tycoon, you are the manager of a fully automated factory. The factory produces consumer products that can be sold for profit on the central market. The factory is fully simulated in real-time.

Terrorformer TD is a tower defense roguelite with a procedurally generated map that YOU shape! Raise or lower tiles, divert enemy paths and funnel monsters into perfectly designed killzones. Randomly drawn cards result in plenty of run variety, as you seek to survive endless waves of enemies.

Hostile Mars is a factory-building game focused on combat! Explore an open world and discover new tech to unlock powerful weapons and structures. Create efficient supply chains using delivery bots. Salvage destroyed enemies for resources. Design your base to withstand increasing waves of enemies!

A tower defense game.In the wave after wave of enemy attacks like a tide, constantly configure defense tower ties, player talents, props and equipment, build a powerful defense position, and eliminate the enemy before they fill the map!

Star Vortex is a fast paced Action-RPG inspired by classics of the genre. Design your ship, fight your way through hostile alien sectors, upgrade as you salvage rare weapons and experiment with different builds until nothing can stand against you.

Neon Colony is an isometric tower defense game where you build your own road to access and harvest the resources of an alien planet. Deal with the resistance of the local population and fulfill this noble mission for your generous corporate benefactors.

Rionag: Survey Fleet is a top-down starship builder and logistics game where it's your job to balance the needs of the crews with cutting-edge equipment on board. Unlock tech that adds new capabilities for your ships to go through hazardous environments, enabling you to explore new worlds.

Infinitory mixes city-building, automation, and tower defense in a in a rogue-lite top-down game. Expand your base vertically in limited space, a strategic planning challenge. Automate resources to produce ammunition and upgrades, crucial for stopping waves of enemies on procedurally generated maps.

A rogue-lite dice game in space! Build your ship as you explore randomly generated star systems, survive hostile encounters, and upgrade your colony ship for the next generation of chasers. Can you find a new home for your orphaned race amongst the stars?

Select unique spaceship models and multiple talents from 80+ options. Explore the world map, complete missions for gold, and shop for items. Defeat foes, earn experience, and enhance your spaceship's modules. Forge your style and prove its strength.

Corporate greed meets strategic planet-mining in Drill Core! Drill to the heart of planets while managing workers, researching cutting-edge tech, and fortifying against alien attacks. Will you prioritize efficiency and risk your workers' safety, or focus on defense for survival?

SUPRACORE is a roguelike base building game. Build your base, upgrade it and defend against ongoing waves of enemies to gather more resources and expand your Core!

Management In Space is a gritty sci-fi strategy roguelite where you find yourself in debt. Build, mine, trade, and defend using stations across the galaxy, all while wars swells, aliens devastate sectors, and cults rip the galaxy apart & release interdimensional demons upon the universe.

The AUTOMATION bullet heaven! Build, automate, autocast, OBLITERATE!

Mineral Defense combines tower defense with roguelite elements and procedural generation. Build paths, unlock upgrades, and unleash powerful synergies to conquer evolving challenges in an ever-expanding world.

Create, manage and grow your energy empire and network in this energy simulator tycoon. Energy Manager is among the most realistic of the strategy genre - so prove yourself and beat your friends and other real life managers.

Defend against waves of enemies with a strategic mix of spellcasting and tower defense. Explore new spells, towers, and artifacts in each run and discover your own playstyle in this rougelike Tower Defense game.

Command a fleet of customizable ships in this roguelite strategy autobattler. Liberate planets to unlock new ships and powerful upgrades. Engage in strategic battles, manage your fleet, and face escalating challenges as you fight to free the universe through increasingly difficult galaxies.

Defend attacks from enemies from all directions within a limited time. Only by making full use of the differences in each tower and choosing appropriate random rewards can you survive.