Top similar games like Dr. Professor Scientist's Weapons Testing Facility:

Be the ultimate CEO and military strategist in this genre fusion of strategy and business management. Create your own company, hire employees, research weapon technology, and take control of units on the battlefield to defend the moon against an alien invasion. Aliens down, profits up!

Towerbloom is a pathless roguelite tower defense with reactive gameplay. Employ countless outlandish strategies and supercharge your towers by hovering over them to vanquish enemies.

SUPRACORE is a roguelike base building game. Build your base, upgrade it and defend against ongoing waves of enemies to gather more resources and expand your Core!

Stop an endless hoard of crystal-type enemies, with different attributes, from reaching the portal to earth! You can build your own labyrinths, unlock new turrets, upgrade them, unlock abilities, and also gather permanent bonuses.

Refactor is a hard-core tower defense game that combines modular building, route planning, and element composition.

Hostile Mars is a factory-building game focused on combat! Explore an open world and discover new tech to unlock powerful weapons and structures. Create efficient supply chains using delivery bots. Salvage destroyed enemies for resources. Design your base to withstand increasing waves of enemies!

Fight waves of enemies and a battlefield that erodes & grows in this roguelike/lite tower defense game! Assemble your home tower, build defenses, terraform the map, cast spells, buy upgrades, and unlock new perks with every run. How long can you survive the terror?

Defend attacks from enemies from all directions within a limited time. Only by making full use of the differences in each tower and choosing appropriate random rewards can you survive.

The Last Starship is a space-based construction, industry & factory game, currently in Alpha (expect regular free updates). Design star ships and take on a variety of missions from mining and passenger rescue to combat whilst working on the greatest engineering project ever attempted by humankind!

Co-op twin-stick base building survival game.

Plow through swarms of aliens! Lunar Loot is a casual incremental game with hints of survivor-like gameplay. Kill aliens, acquire Moonshards, spend those Moonshards, and repeat. It's simple! No death! No stress! Just get rich killing aliens!

Build & defend a small remote mining base on Taichin XI from the alien hordes. Deploy defenses, upgrade your turrets and get ready for the nightfall. The Unearthened is a classic Idle Tower Defense game where you build towers and prepare for the invasion.

"miniBONG" is a lightweight rogue-like game that focuses on dress-up DIY and idle gameplay, while incorporating elements of combat, character development, and strategy.. You can feel the charm of dressing up and fighting at the same time.

Select unique spaceship models and multiple talents from 80+ options. Explore the world map, complete missions for gold, and shop for items. Defeat foes, earn experience, and enhance your spaceship's modules. Forge your style and prove its strength.

Space debris is out of control! Craft a station to take out the trash in this construction roguelite mashup.

Eyeb is an action packed tower defense-like that pits a young space cadet's bionic eyeball against a harrowing nano-bot invasion. Push out, explore, power up and drop a trillion towers for the glory of facing off with the diabolical Nano-Lord. You can also go fishing in space.

Explore the mysterious Wall World on your giant robospider: mine for valuable resources, upgrade your equipment to fight off hordes of monsters, and discover exotic biomes in-between attacks. Will you be able to survive and learn the secrets of the Wall World?

Tower Factory is a tower defense/factory sim game. Optimize resource production with intricate conveyor systems and strategically deploy towers to fend off relentless enemies. Seek out and destroy the enemy castle, unlocking permanent upgrades between battles.

Grow your planetary empire from a small base to a massive production powerhouse in Planetary Factory. Balance inputs and outputs to maximize profits and minimize waste, research advanced technologies, and build a formidable military to conquer hostile planets.

Outgun alien hordes in a short and sweet bullet hell arena shooter. Fight through waves of randomized enemies as you grow increasingly more powerful by acquiring unique upgrades.

Rionag: Survey Fleet is a top-down starship builder and logistics game where it's your job to balance the needs of the crews with cutting-edge equipment on board. Unlock tech that adds new capabilities for your ships to go through hazardous environments, enabling you to explore new worlds.

A Simple Tower Defence Game. Build, Loot, Buy & Sell, Level Up, Quest... Controllable Difficulty, Custom Gameplay, Ingame Help.

A rogue-lite dice game in space! Build your ship as you explore randomly generated star systems, survive hostile encounters, and upgrade your colony ship for the next generation of chasers. Can you find a new home for your orphaned race amongst the stars?

We fused deck-building roguelikes and tower defenses in a way never seen before - deploy your towers, collect valuable trinkets and cast powerful spells to defend yourself against the Salkoth!

Take command of humanity’s last survivors and rebuild an empire in the stars. In this immersive turn-based strategy game, you will have to fight to protect your people, control rival factions, and unlock lost technology.

This "space station builder simulation roguelite" puts you in charge of a space station. Fight off enemy ships, fleets and rival stations to dominate your corner of space. Build and upgrade your station, hire and manage your crew. Survive as long as you can.

Save Our Solar System brings a fresh look on the tower defense genre. Shape the world around you with a lovable playable character. Harvest metal to upgrade towers. Collect rocket parts to advance to further planets. Fend off endless waves of asteroids.

Project Astra Dominium is a Tower Defense game with Basebuilding and Automation elements. Build up your base to become a supply hub for Earth's desperately needed materials, gather resources while defending against an unknown alien threat and improve your tower's and AI capabilities.

Build a formidable factory and go dungeoning alone or with friends. Solve logic puzzles and automate resource collection and crafting, or take a break and explore dungeons filled with enemies and dangers. All progression is entirely separate, so your own unique path is yours to make!

A roguelite looter shooter where you breed guns, craft perks, and choose mutations, creating powerful synergies to defend against the relentless alien hoarde!

Action roguelike horde shooter. Bullet heaven vs bullet hell. Enter The Astral and find powerful guns to slay demons by the thousands, take their power and get strong enough to defeat the Astral Kings.

Become a titan of industry! Simple to learn, difficult to master! A rogue-lite with plenty of charm and simple complexity.

Genome Guardian is a top-down roguelite turret shooter where you must defend yourself from hostile aliens at the microscopic level. Combine & discover 70 weapons across 4 modes using a vast array of turrets, perks, modifiers and power-ups on this vibrant journey to the depths of the abyss.