Top similar games like Prototype TD 2:

Prepare for the onslaught! Chromatrix is a retro tower defense game where color and placement are everything. Upgrade and customize your turrets to counter shifting enemy-types and map configurations. Manage your resources and craft the perfect defense against any attack!

A roguelike tower defense game with a dash of deckbuilding. Choose a reward, improve your build, survive the next wave, repeat. Highly replayable, difficult, and addictive. You'll want just one more wave, just one more run!

Tile Trials is a tile-placing, number based puzzle game for the casual strategist. Place a variety of familiar shapes onto increasingly difficult layouts to maximize your score and surpass each threshold. Roguelike gameplay, mind bending challenges, and hand-crafted puzzles await!

Cute, squishy, and armed to the gills — your mushy defenders are the forest’s last hope against lumberjack invasion! Grow, evolve, and command your Shrooms to protect your unique island home.

A rogue-like sci-fi Tower Defense strategy game with infinite replayability!

Lizard Brain is a game that challenges your memory and puzzle solving skills. Navigate a lethal maze by remembering the correct path before the deadly traps become invisible. As you progress, choose from a variety of challenges that increase the difficulty in chaotic or puzzling ways.

A tactical auto-shooter where you build your own maze! Combine tower defense, roguelite powers, and upgrades to survive endless waves of monsters.

Transistor Defense is a strategic tower defense game where players must fend off the onslaught of a rogue sentient AI determined to overtake the network.

ProtectHeart is a strategic defense game, defend the heart at all costs! Are you up for the challenge?

Isle of Arrows is a Puzzle Tower Defense game in which you build a fortress in the sky. Place towers, expand the isle, and build your own paths. Can you find the perfect spot for each tile to beat the RNG and defend against waves of invaders?

Rogue Cube Defense is a minimalist roguelite tower defense game with procedurally generated path that you gradually build up. Each run is different as the upgrades you get from leveling up are random. Pick your towers loadout and come up with the best strategy to beat the hordes of enemies.

Hallway Defender is a roguelite tower defense where you defend your base from an endless wave of fellow classmates. With over 25 different towers and even more upgrades and effects there are infinite ways to set up your own defenses.

Tower Escape is a reverse tower defense game, where instead of defending against incoming enemies, you play the baddies and guide your minions to the exit. Recruit a team of minions, and collect powerful gems and relics that make each run unique.

Stop an endless hoard of crystal-type enemies, with different attributes, from reaching the portal to earth! You can build your own labyrinths, unlock new turrets, upgrade them, unlock abilities, and also gather permanent bonuses.

A fusion of tower defense games and roguelike deckbuilders. Use your cards to build towers and to upgrade them in unique ways. Gain rewards to customize your deck, defense and playstyle. Break the shapes before they break you!

Junkyard War is a unique take on the tower defense genre. Clear trash from the junkyard and recycle it into valuable resources while holding off waves of your competitor's army trying to make the trash disappear by burning it all down!

Super Sanctum TD is a retro-styled Tower Defense game that focuses on strategy, customization and replayability. Build advanced mazes and construct powerful towers to prevent alien hordes from reaching the Core!

Nightmare has set its sights on this world, and as the will of the world, you will rely on cards, tower defenses, and urban construction to destroy Nightmare's invasion in the dream

Play the first deck of Shapebreaker for free. A fusion of tower defense games and roguelike deckbuilders. Use your cards to build towers and to upgrade them in unique ways. Gain rewards to customize your deck, defense and playstyle. Break the shapes before they break you!

Kofoin is a real-time Tower Defense game where you command your swarm of bees, expand your territory, use powerful flowers to upgrade your defenses, and harness the power of Basque divinities to survive hordes of enemies

Tired of boring common square levels? Finally there is a brand new minesweeper with different game modes! Each level is a part of collection. Complete collections to obtain keys and gain access for more episodes. Achieve higher levels to unlock new items, chests, pets and much more!

Mega Deal Card is an addictive card roguelike. Match cards on a 3x3 board, use special cards to create explosive synergies, and unlock unique decks that reshape every run. Enhance your strategy with new cards, passive perks, and varied minigames.

Qubicks is where tower defense meets roguelike as you venture across procedurally generated levels where you strategically position towers, balancing immediate survival with long-term growth. Upgrade your towers and heroes to adapt to difficult waves and ensure victory against alien inhabitants.

Dawnhelm Defense is a strategic tower defense game set in a medieval-fantasy world where players must defend the mighty fortress of Dawnhelm from relentless waves of enemy invaders. You will build and upgrade powerful towers and deploy magical abilities to stop hordes of enemies.

Defend the energy cores from ever increasing enemy waves by destroying their spawn gates. Build tower mazes on Hex grid. Adapt them to dynamic changes in the terrain. Face quirky bosses. Design your own levels and share them on the Steam Workshop.

That Makes Sense is a puzzle game where you define the rules to solve puzzles. Challenge yourself to think in familiar and new ways to creatively solve the puzzles.

Box Stocks is a Sokoban game about a robot in space solving puzzles with boxes with unique and peculiar interactions. Sort your way through the galaxy while uncovering the secrets of the mysterious yet inept company that left you and the boxes behind.

Play as a young Ted Kaczynski, experiencing first hand the horrors of the MK-ULTRA program in this highly unique psychedelic tower defense game.

Relax and listen to the hypnotizing world of Oxytone, slow paced puzzle game where you rotate hexagonal tiles with paths. Each tile can be used up to six times, creating tangled paths.

Defend your base from all directions in this no-path tower defense. Build, upgrade, and adapt to unpredictable enemy waves, survive unique boss fights and unleash the Quantum Decimator when things get overwhelming.

Customize your army and control the battlefield in this challenging turn-based tactics game with roguelike progression!

Tower defense reimagined! Dead Ground is a procedurally generated tower defense game with rogue-like elements. Each playthrough will offer randomly generated guns, skills and augments. You'll have to travel, collect scrap, water, manage your inventory and upgrade your base to survive!

Explore, build, harvest. Hexton is a relaxing building game where you try to create the largest city possible. Looking for a light challenge? This game's for you!

Classic tower defense meets roguelike adventure where you control the hero! Dive into procedurally generated levels filled with unique waves of enemies. Create powerful synergies with a variety of game-changing skills, relics, weapons, and traits to defend your kingdom. Every run is a new challenge!

Doodle TD Is back and better than before, Place and smack enemies down with force in this brand new tower defense game. We added color from the original game as the evil mastermind has colored the world of doodle land.