Top similar games like Main Sequence:

Factory Trashcension is a first-person open-world factory creation and optimization game with unlimited possibilities. Play with your friends and design efficient factories to TRASHCEND without worries and explore a v a p o r w a v e inspired universe!

Factory management and sandbox base building in zero-g environment. Survive, expand and then dominate space industrial market. Build large scale resource processing plant completely from nothing.

The Universe is yours. SpaceCraft is an online space exploration and building game. Explore a vast galaxy of solar systems and planets, mine and craft resources, design and build ships, automate planetary bases and interplanetary logistics, trade and cooperate.

Satisfactory is a first-person open-world factory building game with a dash of exploration and combat. Play alone or with friends, explore an alien planet, create multi-story factories, and enter conveyor belt heaven!

Create an automated system that terraforms a planet with an army of drones. Craft and build bases, set up a weather monitoring system, prepare to survive different types of storms, and take control of the climate and biomes!

Build the most efficient intergalactic factory in space simulation strategy game Dyson Sphere Program! Harness the power of stars, collect resources, plan and design production lines and develop your interstellar factory from a small space workshop to a galaxy-wide industrial empire.

Explore endless Universe and create the most efficient constellation of colonies. Build conveyor systems to automate production. Take care of Astronauts and their needs! Establish new colonies as part of intergalactic simulation.

LithoBreak is a survival factory-builder grounded in real physics and engineering. Build and automate a lunar colony, explore in first-person, and survive constant orbital threats – all while you Play with Science

Choose your own adventure in this open-world humanity expansion space simulation. Travel beyond the constellations to new frontiers. Explore, collect resources, supply the expansion efforts, or go battle it out spaceshooter style. Do we seek Galaversal Supremacy or peace? You decide !

You were deep in uncharted space on a research mission. Disaster struck. Together with your friends, explore a mysterious asteroid field and mine whatever resources possible to build what you need to survive.

Survive, craft, and automate in this free prologue set on one of the planets you can transform in Eden Crafters, an open-world game where you play solo or with friends to turn a hostile planet into a habitable haven for humanity.

A retro-future sandbox RPG set in a frontier era galaxy with procedurally-generated elements. Create, explore, trade, and battle to stake your claim among the stars of a wild galaxy!

Techtonica is a first-person factory automation game with a gripping mystery about mining your way out from the depths of an alien planet. Explore bioluminescent caves, mold destructible terrain, construct a massive subterranean factory. Dig your way toward answers & discover the secrets of Calyx.

A first person building game where every problem is solved with pipes.

Astrometica is a space exploration and base-building survival game. After a catastrophic event, explore vast space, gather resources, build bases, and uncover cosmic mysteries. Use advanced technology, craft tools, and discover new blueprints to survive and thrive in the unknown.

Craft your workshop as an alchemist!‌ Harness arcane devices to automate crafting. Sell alchemical goods, fulfill commissions, and rise to become a renowned alchemy magnate. ‌Multiplayer Supported!‌ Invite master designers to (ahem) contribute their expertise—let them optimize your production lines!

Experience the first stages of terraforming an entire planet in this space survival open world terraforming crafting game prologue. Explore, survive, collect, build your base then create oxygen, heat and pressure to make an hostile planet livable for humanity.

Dig sand with a shovel and process into iron, silicon and more. Craft and merge better tools and machines to build solar panels and power your factory. Research new machines to automate everything in voxel-based multi-story factories. Play alone or with friends and turn the desert into a solar farm.

After a century in cryosleep you find yourself stranded amidst the ruins of mankind’s first interstellar colony. Explore derelict ships and stations and harvest raw resources in search of air, fuel and other equipment. Or loot and pillage what you need from other survivors. The choice is yours!

A survival engineering game where you build life support habitats, mine resources, and automate production chains on a radiation heavy planet. No rescue. No support. Just engineering.

Set on small procedurally generated planets, PoliPlanet is a unique first-person city building game. Discover new planets, gather resources, craft, explore, and build.

A sudden, devastating strike has reduced your interstellar voyage to ruins. As the sole survivor in X SPACE, you must rebuild your space base from scratch, assemble a versatile fleet, and pilot your massive mobile fortress into the depths of the universe.

This is a voxel style sandbox game that focuses on survival. You can do anything inside and destroy any block. and cooperatively survive and fight with friends in a world. If you like playing Minecraft, this is a game you must not miss.

Railborn is a survival game where you build your train piece by piece. Navigate a world entangled by branching tracks. Find rare plants to cultivate on your farms. Upgrade your train - manage its power systems, direct resource flow, and distribute water. Designed for 1 to 4 players.

Build, host, and survive in a persistent multiplayer space sandbox set in the outer Sol system. Construct orbital habitats, manage fragile station systems, and keep your crew alive while expanding through zero-g, Saturn-ring danger, and player-built infrastructure.

A sandbox survival game, set on life-sized voxel planets with realistic physics with the possibility to shape your own building blocks. From your custom made furniture, walls to vehicle parts. You shape the blocks which can then be used to build buildings, spacecraft and aircraft.

Haul Yeah! is a chill co-op space trucking game. Live aboard your ship, grow food, cook meals, deploy drones, repair hull systems, trade on a player-driven market, and haul resources across 15 star systems. Play solo or with up to 3 friends via Steam.

Dawn Apart is a space colony and factory sim with fully destructible environments. Mine, automate, and defend your settlers, or lead a rebellion against the very corporation pulling your strings…

Build a self-sustaining industrial empire in the deep sea of an ocean-covered alien world. Explore procedurally generated waters, automate resource production, and turn alien life into renewable industrial output through advanced bio-cultivation systems.

Return to an Earth abandoned for over 500 years and explore its transformed oceans in search of vital resources. With supplies on humanity's new home world running dry, you must gather materials, build automated underwater operations, and uncover the secrets that now lie beneath the waves.

Stranded on a hostile alien world, you must gather resources, craft tools, and automate production to survive. Build a base, fend off deadly wildlife, and uncover ancient secrets in this immersive sci-fi survival adventure. Will you conquer the planet or succumb to its perils?

"Illegal Simulator" puts you in the midst of two different lives. While running a legal market during the day, you'll manage illegal casinos and harvest banned substances at night. Collaborate with mafia gangs, have fun at strip clubs, and become the most famous figure in the underworld!

Stardeus is a deep colony sim set on a broken starship manned by drones and hibernating human survivors. As the AI, have your drones repair your ship, save your crew and travel the stars in this beautiful simulation.

Moonshiner Simulator is an in-depth spirits production simulator. Start from the bottom and build your operation into a thriving empire by mastering the intricacies of the craft and creating unique recipes. But beware – there will always be those who want to see you fail.

Astrometica: Prologue is the free game about surviving in space. You need to use your skills and tools to stay alive. There are many challenges to face, and you need to fight to survive. You also need to build a new base in space.