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Xenomycology
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The top results based on the latest update are Bloodtide Tower Defense [Score: 0.8], Tomb Of AnuBI0S [Score: 0.8] and Super Sanctum TD [Score: 0.8] The top rated games you can find here are Creeper World 3: Arc Eternal [SteamPeek Rating: 7.8] ranked #4, Let Them Come [SteamPeek Rating: 5.9] ranked #23 and Super Sanctum TD [SteamPeek Rating: 5.9] ranked #3 Also don't forget to check the newest releasesSolar Defense [Release date: 2026-03-13] ranked #20, Bloodtide Tower Defense [Release date: 2025-12-05] ranked #1 and Dungeon Warfare 3 [Release date: 2025-08-29] ranked #19 While it is tempting to play with the newest and the best, there might be some other gems in the results, like 重构 Refactor [SteamPeek Rating: 5.1] ranked #17, Dungeon Warfare 3 [SteamPeek Rating: 5.1] ranked #19 and Let Them Come [SteamPeek Rating: 5.9] ranked #23.
Xenomycology is a metroidvania tower defense game. You control a colony of extra-terrestrial fungus spreading across a planet, and fighting off invading creatures. Xenomycology also offers a peaceful mode if you only want to grow mushrooms and explore the world.
We've traveled to the past to conquer these fertile lands. Now, you must defend them from the blood cult intent on taking it for themselves. Be careful though: from where their blood is spilled, ancient magicks empower whomever is still alive.
Tomb of AnuBI0S is an unique 2D tower defense-platformer with an Egyptian Sci-fi setting. Defend the AI deity RAm from waves of undead "Organics." Upgrade your arsenal from weapons to walls, turrets, and your player capabilities. Immerse yourself in meticulously crafted levels and defend RAm!
Super Sanctum TD is a retro-styled Tower Defense game that focuses on strategy, customization and replayability. Build advanced mazes and construct powerful towers to prevent alien hordes from reaching the Core!
Creeper World 3 is what happens when cellular automata takes over a strategy simulation. Instead of discrete units that attack your base, a fluid-like substance spreads over the terraformable terrain. Your base, your weapons, your strategy... you must adapt them all.
Build towers and learn abilities to defend against swarms of hundreds of on-screen hostile alien creatures. Choose between sets of randomized upgrades that both upgrade you and the alien swarm. From enormous explosions to far-reaching flamethrowers, no two games are the same.
Project Astra Dominium is a Tower Defense game with Basebuilding and Automation elements. Build up your base to become a supply hub for Earth's desperately needed materials, gather resources while defending against an unknown alien threat and improve your tower's and AI capabilities.
Build, automate, and defend humanity's last factory on a dying industrial planet. Chain production lines, survive AUTON raids and dust storms, research lost technology, and uncover what silenced every factory before yours.
Tower defense / Roguelike / Sci-Fi / Pixel Art game with boomer games aesthetics. Mine resources and shoot those disgusting aliens right in their faces. Unlock new technology, develop new strategies and explore the planet. A modern old-school Pixel Art experience with the vibe of 90s classics.
A Roguelike Tower Defense in space with missions to conquer. Can you hold against the spreading alien bosses? Build and upgrade towers against the corruption. Choose your technologies and warpspeed your way to victory.
The Rebel Space Admiral is an idler/ clicker game about space exploration with battles, trade, base building, planet invasions and science research. Fight your way through hundreds of star systems, meet aliens, find powerful artifacts and defeat an ancient evil before it purges the galaxy.
You build and command an orbital starport caught in an endless war zone. Pirates, meteors, and cosmic anomalies strike without pause. The galaxy doesn’t grant peace, only those who build through the fire survive.
"In 'Random Core Defense,' acquire and enhance cores using limited resources to withstand relentless enemy onslaughts. Defeat powerful bosses and test your strategy to survive until the very end!"
Build & defend a small remote mining base on Taichin XI from the alien hordes. Deploy defenses, upgrade your turrets and get ready for the nightfall. The Unearthened is a classic Idle Tower Defense game where you build towers and prepare for the invasion.
A 2D pixel art tower defense game with unparalleled strategic depth. Deploy modules to redirect enemies, use tactical chips to command the battlefield, and upgrade towers with multi-branch modifications to protect humanity's vital Stellacore energy.
Solar Defense is a Military Sci-Fi inspired Tower Defense game focused heavily on strategy and decision making. Defend key locations and repel the Pilakarr forces back to their home world to end their attack and bring an end to this war.
Inspired by modern science fiction! A modern real-time war game, the screen is in the style of realism, the fast-paced attack effect is easy to fatigue, easy to use and simple to operate, mainly in the traditional style
Scrap Bastion is a strategy tower defense game where you manage your city, equipping it to survive the waves of mutant creatures, testing your planning and decision making capacities at every turn. Watch out, as time is crucial to win!
Let Them Come is a fast paced pixel art shoot ‘em up. Twitchy trigger fingers and focused battle tactics are the order of the day as wave after wave of alien-like creatures try to take you down.
Invader TD is a side scroller tower defense, where the player is in the role of an alien race with the purpose of infecting and dominating the earth, you must protect yourself from the attacks of the humans, who are trying to destroy you.
Planetary Defense: An Orbital Turret Defense System
1.1 3 0
11 Aug, 2022
RS: 0.73
2D space shooter and turret defense come together to create the Planetary Defense System this world needs! Shoot down asteroids and aliens and survive the bosses in this arcade like game featuring customizable satellites, projectiles, and upgradable Cannon and Planet Shield systems.
Liberator TD is a glorious mix of tower defense and top down shooter genres set in a sci-fi world. Tasked with the mission to establish a new colony on a distant planet, you find yourself in grave danger of the local wildlife.
A pixelated 2.5D RTS meets tower defense as you battle mutated ants in a short campaign. Build walls, place turrets, and hold the line to reclaim Earth's surface in this tactical fight for survival where placement of everything matters.
Defend your castle from the attacks of the night creatures. Collect coins, interact with the elements of the game, discover, explore, learn and survive for 30 days or try again.
Bestion is a game that combines Roguelike tower defense elements with automated factory construction. Players are required to construct their own factory on a planet and protect the kernel from monster attacks.
Jishin, is a tower defense game where the ground is anything but stable. As waves of relentless enemies surge towards your base, you'll not only need to strategically build towers, but also adapt to the ever-shifting battlefield.
Tower Defense meets a Visual Novel narrative. Place an arsenal of towers to halt the invading enemy. Use special abilities such as napalm strikes, EMP blasts, and orbital lasers. A sci-fi space drama, filled with dialogue choices.
Build, Upgrade, and then Move your Towers in this unique twist on the Tower Defence genre. With Rogue-Lite mechanics every run offers new strategies, and every death unlocks new upgrades. Grow. Evolve. Destroy the Robots!
Control your Hero to aid your Turrets and Traps in battle in this grim, dark Tower Defense & Action RPG with a scifi-grindhouse aesthetic. Create deadly weapon barrages and fuse together Bleed, Burn, Shock, Freeze, Stun and many more elements to annihilate your enemies.
Get ready for an epic pixel art showdown ! Dive into the heart of tower defense chaos as you battle against scrumptious calorie-packed enemies, all on massive, sprawling maps. With an extensive arsenal of towers at your disposal, it's time to defend against the ultimate sweet tooth invasion!
Atlanta TD is a roguelite tower defense game where the armies of the underworld descend onto the Four Spectacular Realms in waves as it falls unto the remaining Gods to protect the city of Atlanta!
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