Top similar games like Xenomycology:

Astra Sentinel is a real-time strategy game in which you must defend planetary systems from endless hordes of aliens. Reconquer planets, build on their surface and prepare to counterattack. Will you be able to recover the control of the galaxy?

Desperate Place is a strategic tower defense game where you play as a crew member who wakes up early on a damaged colonization starship. Stranded on an unknown planet, you must gather resources, repair the ship, and defend against alien monsters to survive and escape.

Take action in this immersive 3D experience where you can build your own village, command your troops into battle, and plunder resources from enemies.

Deep integration of city builder and tower defense. Time is the most crucial resource in this world. Lead your clan to construct a base in the dazzling circuit world and fend off waves of enemy attacks!

A minimalist game about building and defending your little kingdom.

Paddle Protectors is a mix of tower defense and real-time strategy (RTS). You will fight against crabs, bugs, and more. Establish farms and factories to produce ammunition and resources, fortify your land , build trenches and towers, lead your soldiers and tanks, and research new units.

A 2D Strategic Base Defender game set in Medieval times. As relentless Waves of enemy forces threaten your Stronghold, you must gather Resources, Fortify your Defenses and lead your Rebellion. Prepare to strengthen your Base and manage your Resources. But beaware of the Storms!

Action adventure strategy game with tower defense, in a fantasy world, use your own combat skills, weapons, and the power of your partners to survive. Face the ultimate fate with your unique combat style.

Hive and Seek is a side-scrolling strategy base-building game where you clear randomly generated Roguelike stations infested with monsters. By rallying robots and clearing rooms, you will be able to destroy hives and recapture the station piece by piece.

Tin Lord is a fast-paced action RTS in a post-apocalyptic world where you control robots that rebuild technology and fight monsters in a destroyed world.

In this city builder and tower defense game, you will command a small band of ship wrecked colonists. Progress from struggling to survive the elements to a thriving kingdom that will smash the demon hordes that dare attack your settlement.

Diplomacy is Not an Option is a strategy game set in a medieval fantasy world. Build your town and defenses, raise huge armies and fight against massive hordes of enemies. How long can you survive?

A minimalist game about fighting for freedom and independence in the United States of America!

A brutal godlike village sim that melds the god game, management, and tower defense genres! Fight off hoards of monsters at night, and expand your village in the day time. Inspired by games like Black and White, Rimworld, and Dwarf Fortress but not quite like any of them.

Scrap Bastion is a strategy tower defense game where you manage your city, equipping it to survive the waves of mutant creatures, testing your planning and decision making capacities at every turn. Watch out, as time is crucial to win!

Tendrils and Plates is an Open World Sci-Fi Space Survival Shooter RPG under development by a solo indie developer. You begin in a scout starship and learn to survive in a hostile solar system. Build your base and take on missions in space and on numerous ground locations.

Diplomacy is Not an Option: Shareware is a free prequel to the original game. In a medieval fantasy world, you are to build settlements, raise huge armies, and defend against massive hordes of enemies. Learn how Ironbrow clan shaped the world's map the first time - if you survive, that is.

Chaos Islands is a city-builder that unites deck-building and tower defense mechanics with roguelite elements. As the last bastion of humanity forced to escape to the skies to hide from invading forces of demons. Protect your settlement and do not let the evil forces pass.

you will play as Gaia, the shattered will of a planet, and command your spaceship to explore new worlds, collect and refine various resources, build a home on the damaged spacecraft, summon a wide range of monsters, and ultimately, devour other shattered wills to repair yourself.

In this city builder, build a city and defeat invading bugs, but don't squish your own civilians.

Post-apocalyptic city builder, where you Build, Defend, and Thrive in a desolate landscape overrun by enemy attacks. Manage resources, production and manufacturing to expand your settlement.

Lead your kingdom to victory! By day, you build and prepare your kingdom for impending threats. But every night, you must defend your kingdom against hordes of monsters, by commanding soldiers, building turrets, and fighting on the battleground yourself.

Immerse yourself in Nordhold: Origins, a tower defense game with high replayability. Build a medieval Nordic village, develop its economy, and defend it with unique towers and upgrades. Choose heroes and relics, compete on leaderboards, and aim for the Valhalla rank!

Create the perfect community for your town of wizards. Forge weapons and defensive towers in preparation for the onslaught of monsters - and pray you survive.

Protect your cities against waves of enemies. Manage your resources and plan accordingly to develop your city and armies to survive!

Last Hope Of Pirates is a thrilling tower defense game where players defend their sea bastion from waves of enemy ships. Upgrade defenses, command your pirate ship, and strategize to fend off ghost fleets and invading flagships. Experience the ultimate challenge of pirate warfare.

World of Towers combines puzzles with tower defense. Design your base in order to collect all of the puzzle pieces and destroy your enemies. Create and share your own worlds on the Steam Workshop using the World of Towers World Builder

Alpha Lyrae (Vega) is the brightest star in the northern constellation of Lyra. You were sent to Alpha Lyrae system, and your first object is to discover and to transmit data back. The last and only message from the previous team: "It is a rich and soft planet. They are everywhere."

Endustry is a game about building, exploring and surviving. Build machines and conveyor belts to collect resources. Try to survive with or without enemy waves depending on which game mode you play.

NecroCity: Prologue is just part of the gameplay that awaits you in the full version of the game. Take on the role of the young Prince of Undead, trying to prove himself in the world of the Undead Kingdom. Push back the hordes of monsters and build your fortress! 🔥

Gather resources and strategically build up your Viking settlement by day, fortifying it to withstand the relentless onslaught of skeletons by night

Islets Defense is a turn-based tower defense game where you build a small village to earn resources and defend your castle.

The creeper is flowing through canyons to your base while you rush to build a space station in 3D by sending packets to your building foundations and pushing the fluid back with your weapons, eventually capturing the sources of the enemy or being drowned by it.

Create, upgrade, and customize your very own Bloons Monkey City in this groundbreaking blend of city building and tower defense awesomeness!

SpiderPunks is a unique blend of three-game genres: Builder/Defense, Action, and Puzzle. Earn money and spend it on new spider's web connections. Buy new spiders or heal injured ones. Get experience to develop more spider's skills to fight against toxic soap bubbles.

Throneforge - The Fortress War:Build an arsenal of diverse towers, each with unique abilities and strengths.Strategically place towers along the enemy's path to maximize their impact and create impenetrable defense lines.