Top similar games like Space Annihilator:

Tower Tactics Arena is a fast-paced action roguelite set in the Tower Tactics: Liberation universe. Battle relentless enemy waves in a closed combat arena, level up your towers strategically, and gather powerful trinkets and potions! Will you claim victory in the arena?

Build, customize, and unleash your ultimate space platform in NebulArena, a fast-paced, fully automated PvP arena where strategy, design, and destruction collide!

Endless Coffee is out! Build your ship, survive 21 Days and break the Universe- Astro Prospector is an incremental bullet hell about mining coffee and fighting SpaceCorp. Collect resources, upgrade your ship and become unstoppable. Return AstroCoffee to humanity!

This "space station builder simulation roguelite" puts you in charge of a space station. Fight off enemy ships, fleets and rival stations to dominate your corner of space. Build and upgrade your station, hire and manage your crew. Survive as long as you can.

Breach. Fight. Loot. Repeat... Breach Squad is a top-down sci-fi auto-combat roguelike RPG built around corridor breaches. Your squad fights on its own - you command, manage loot, and grow marines permanently… But if they die, they’re gone.

Full Thrust, Full Inertia, Full Auto! FOXFIRE is a top-down sci-fi survivors-like with space physics and a devastating arsenal of evolving weaponry. Customize your ship and tear through alien swarms as routine recon missions descend into bullet hellscapes.

A Roguelike Tower Defense in space with missions to conquer. Can you hold against the spreading alien bosses? Build and upgrade towers against the corruption. Choose your technologies and warpspeed your way to victory.

Towerbloom is a pathless roguelite tower defense with reactive gameplay. Employ countless outlandish strategies and supercharge your towers by hovering over them to vanquish enemies.

Star Armada is a spaceship auto-battler where you assemble and command a fleet of capital ships and fighter squadrons. Unlock powerful new ships and outfit them with a range of turrets, energy shields, and starfighter hangars. Engage in automated battles, carefully timing unique abilities to win.

Build by day, hold the line by night. A pixel-art roguelite where you raise a village, recruit heroes, and watch your formation hold or break against waves of monsters in real-time auto-combat. How long can you hold the gates?

Hold on in the Dungeons - Time to Hunt

Prismachines is a roguelike, stationary, horde-survival, autobattler. Draft a team of geometric shapes, equip them with game-breaking trigger items, and position them on the grid. Watch your automated engine of destruction unleash screen-clearing chain reactions to survive 20 escalating waves.

Build an army to fight absurdly large numbers of barbarians in this strategy roguelike, with an incremental twist.

Build your city block by block and defeat waves of mechs in this tower defense roguelike! Combine powerful cannons with unique effects to survive the unforgiving wasteland and explore the underground to gather resources and find powerful relics.

An incremental RPG where your deeds shape the world your next life inherits. Live many lives, from youth to old age. Choose your origin, explore a world of secrets, fight hordes of enemies, and etch your name into legend. Time is precious; history forgets those who squander it.

A minimalist sci-fi tower defense. Buy soldiers and upgrade them, defeat waves of enemies, hold your lines.

Build and automate your outpost to survive enemy waves. Fight with powerful guns, place walls, traps, farms and factories, hire units to defend your base, and level them up between runs or lose them forever when they die.

The fusion of deck-building roguelike and tower defense returns, bigger than ever! Build your deck with powerful new cards, unlock unique trinkets, and deploy enhanced towers to overcome relentless waves of enemies and new strategic challenges.

Command a fleet of customizable ships in this roguelite strategy autobattler. Liberate planets to unlock new ships and powerful upgrades. Engage in strategic battles, manage your fleet, and face escalating challenges as you fight to free the universe through increasingly difficult galaxies.

Defend your planet from relentless stream of incoming asteroids in this fast-paced 2D tower defence game. Strategically place defensive buildings and upgrade your arsenal to protect your world from destruction!

TurretFall is a fast-paced roguelite tower defense game. Build and manage your base, collect powerful upgrades, grow your economy, and survive relentless waves of enemies and challenging bosses.

Sci-fi rogue-like mining/tower defense game. Mine through a procedurally generated world to discover artifacts. Defend your spaceship from waves of enemies. Discover and spend resources to improve your mining and spaceships combat ability.

Design your defenses, build your module board, and manage your wires. Combine signals and create synergies to empower your weapons and survive in this base-defense roguelike auto-battler.

A corner screen incremental brick-breaker where bouncing cores destroy endless swarms. Let it run in the corner of your screen while you work or jump into fullscreen and take control yourself. Unlock new Cores, expand your skill tree, survive endless waves.

Refactor is a hard-core tower defense game that combines modular building, route planning, and element composition.

Defend. Upgrade. Dominate. A relaxing incremental base-defense game, packed with powerful skills and a deep skill tree.

An idle survivor-like that sits in the corner of your screen.

Do you like Tower Defense and also clicking the cursor? Then defend your castle with itself and with your cursor. Each castle has its own unique upgrades. Complete stages unlock different castles and upgrade your cursor skills.

KNOW YOUR ENEMY. FIRE YOUR CANNONS. A spaceship management and combat game. As the Captain of Silver Wolf, command your crew and use your energy strategically. Change your future with your decisions. Arm your ship and strengthen its shields. Survive in the solar system full of dangers.

SUPRACORE is a roguelike base building game. Build your base, upgrade it and defend against ongoing waves of enemies to gather more resources and expand your Core!

Build, gamble, and most of all survive in this roguelike tower defense where everything is a tile. Use the slot shop to draft towers and physical upgrade tiles to buff your grid. With hundreds of unique synergies, will you hit the jackpot or let the enemies break your base? Play the odds today!

“Pattern Survivors: Bullet Hell” — a dynamic roguelike where you design your own attack patterns and defend your tower against endless waves of enemies. Upgrade, modify, and adapt your strategy in real time — can you survive the chaos of patterns?

A tower defense game.In the wave after wave of enemy attacks like a tide, constantly configure defense tower ties, player talents, props and equipment, build a powerful defense position, and eliminate the enemy before they fill the map!