Top similar games like The Book of Plagues 2:

The city is drowning in Plague. Panic, hunger, and fear are tearing it apart. You are the last one who can change its fate: heal it, hold it back from collapse… or drive it to ruin with your own hands!

An antidote shop simulator in Paris. Who will you save: your son, who cynically kills unwanted people, or a mad fanatic who poisons people for the sake of "rebirth"?

Crave New World is a strategy sim about building an addictive drink. Buy compounds, rebuild the formula, collect Thirst from demand, open routes country by country, and turn consumers into addicts before Heat brings the operation down.

COVID SIMULATOR is an outbreak simulation that visualizes how quickly Covid-19 spreads, becoming a disaster. The game is an open sandbox where you can add (or remove) Covid mandates and see what happens! Create your workplace, enact your mandates, and roll the dice with your workers.

Patient Zero: Plague Idle is an idle / incremental outbreak builder where you create the perfect pathogen through mutation trees, global infection, long-term upgrades, and new pathogen unlocks. Turn the world into your lab.

Run a street food stall that the Regime gave you, in a country the Regime runs. No one will go hungry, the government says so. Cook, serve. Talk to your customers, and sometimes to the people who come to threaten you.

Running an international organization called the Global Quarantine Bureau, dealing with pandemics and public health issues worldwide, while also ensuring increasing revenue and personal enrichment.

Weed Inc. is a global strategy simulation. Build a cannabis strain from fragments, introduce it to legal markets, and spread it country by country. Turn Consumers into Addicts, contain the Side Effects, and stay ahead of an escalating Global Response.

Experience a day as a Physician during the world's biggest epidemic of the century. Use medical equipment to diagnose and treat patients, make critical decision under pressure. Save as many as you can. You will be monitored on performance.

30% of our society suffers from psychological problems. Many famous people throughout the history and pop culture were troubled this way and required professional help.

2 in 1, Swipe cards to face the deadly virus threat in this story driven strategy game. Step into the world in which you will face the decisions that world leaders make in the event of a deadly virus threat. Every decision have consequences. Create Vaccine in special Arcade mode.

A top-down plague simulation RPG set in a living medieval tapestry. Play the last apothecary in a dying town treating the sick, containing the outbreak, and navigating the politics of factions who'd sooner see you burn.

In a city where death lingers in the air, you are the last one who can resist it. Put on the plague doctor’s mask and fight the plague before it reaches you.

Build, manage and optimise intergalactic hospitals! Recruit staff to satisfy the whims of various alien species, and cure their bizarre illnesses - for money! Save the (literal) Galaxy in story mode, or head into sandbox to design the hospital of your dreams.

Craft bio-weapons, master lethal science, and unleash global annihilation. Experiment. Fail. Adapt. Evolve. Repeat until humankind falls.

Prison Pocket Patrol is a co-op prison guard simulator. Search, scrub, and sort incoming inmates according to the warden's strict orders. Deal with brawls, turn a blind eye for a bribe, and pocket confiscated contraband to fund shiny new checkpoint upgrades!

In a dying town where boxing is the last stand of entertainment, you hold the judge’s pen. Bribes, threats, and loyalties will decide whether you live to judge another day… Or get knocked out cold. Split Decision is a tense narrative game where every point makes a difference.

Papers, Please in an SCP-inspired setting. You're an agent of a secret anomaly control bureau. Examine dangerous artifacts, conduct experiments and decide their fate. Keep the world from descending into chaos.

Rescue Operations Simulator is a game where you play the role of USAR (Urban Search and Rescue) member and a team leader. You will arrange and execute rescue operations from real life catastrophic events that shocked and changed the whole world.

Chase, forecast, and document powerful storms in an open world of cities, suburbs, rural communities, and open plains. Track developing weather, capture dangerous events, and survive tornadoes, hail, and destructive winds.

In a not-too-distant, retro-future world shaken by a shortage of medicine, a talented pharmacist is accused of murdering Patient Zero. He flees to the slums, where he tries to survive in isolation until he can recreate the formula for the drug that will save his life.

Restore a damaged underwater station through hands-on maintenance. Repair pipes, electrical systems and machinery, replace physical components, clean abandoned sectors, and gradually bring the facility back to life in an atmospheric first-person simulation.

🍖 Fry meat, stack buns, and serve sketchy customers fast. 💵 Set prices, upsell extras, or pocket shady bribes. 🕶️ Handle weirdos who want ketchup… or chaos. 📼 A gritty, lo-fi PS2-style hotdog sim with janky charm.