Top similar games like Essence Defenders:

Space Run is a «real-time spaceship construction strategy game». Space Run takes the well-known Tower Defense-style gameplay and twists it, challenging you to manage and protect a spaceship and its cargo against the hazards of deep space!

A hybrid card game and tower defence where the hands you play become the towers you build. Defeat the enemies approaching the bear's den and find modifiers that support the elements of your defensive strategy.

Do you like Tower Defense games with Strategy elements? Well, look no further! We've got exactly what you're looking for! Get ready to defend your settlement from enemies using a huge arsenal of towers!

Creeper World 3 is what happens when cellular automata takes over a strategy simulation. Instead of discrete units that attack your base, a fluid-like substance spreads over the terraformable terrain. Your base, your weapons, your strategy... you must adapt them all.

"You are outgunned. You are massively outnumbered. You must win." These are your orders. Humanity has already fought its war against the machines -- and lost. AI death squads stand watch over every planet and every wormhole, the few remaining human settlements are held captive in orbiting bubbles, and the AIs have turned their...

Defense Grid: The Awakening is a unique spin on tower defense gameplay that will appeal to players of all skill levels. A horde of enemies is invading, and it's up to the player to stop them by strategically building fortification towers around their base.

An epic, challenging tower defense game with an emphasis on strategy and replayability. Summon gems of immense magical potency and harness their unique abilities against a seemingly endless horde of monsters. The archdemon seeks to swallow the world, and you must journey to stand against her.

Join in on the next gold rush and become a prospector in space. In this unique tower defense you can set up and reposition towers for maximum efficiency and adapt to the environment.

Fight off hordes of monstrous mutants created from a strange cataclysmic event in the new tower defense game, Prime World: Defenders. Join a group of exile treasure hunters who have ventured into the capital of an ancient empire, vast with mystery and danger.

Spectral Realm is a top-down tower defense Rogue game, where players need to play the role of an astronaut who has just landed on a different planet to block a constant stream of attacking native creatures and continuously strengthen themselves with the gems contained within their bodies.

Build orbital rail systems, combine trains, turrets, and weapons, and defend hostile planets against overwhelming swarms. Every run offers chaotic build variety, explosive firepower, and endless strategic possibilities.

MILLIONS OF ALIENS WILL DIE!Radiant Defense is a tower defense game set in a vibrant universe invaded by countless alien hordes.Build your space fortress any way you wish, set up wide variety of weapons and traps and let the invasions begin!

Immortal Defense is a story-driven tower defense game in which you give up your body and life to become an immortal "path defender", and defend your home world from destruction, forever. The game takes place over millions of years. Is there anything you would give up everything to defend?

ENDLESS Space™ 2 is a Strategic Space Opera, featuring the compelling “just one more turn” gameplay, set in the mysterious ENDLESS Universe™. As the leader of your civilization, will you impose your vision and build the greatest stellar empire?

Co-op and Single player Tower Defense genre.

Taur is an action-strategy sci-fi game. Control the Prime Cannon and unlock all of its powerful weapons and abilities. Build turrets, droids, aircraft and more as you fight to protect the homeworld of the Tauron droids against a relentless invasion. Will your Taur stand against the Imperion warmachine?

Defend the solar system from fearsome aliens by sending satellites into orbit in revolutionary tower defense action!

Valdis est un hybride dynamique tower defense et third-person shooter en univers sci-fi. Défendez le noyau énergétique d’une station spatiale contre des vagues de zombies, combinez tourelles et éléments, déclenchez des réactions dévastatrices et survivez avec votre fusil à pompe !

Build and design your own fleets and stand opposed to the Particulate in this physics/strategy/RTS/fleet hybrid. Build partially destructible and self repairing ships that interact with enemies less controlled by some scripted logic and more driven by a real time massive physics particle simulation.

Slice them, burn them, skewer them, and launch them - no matter how you get it done, orcs must die in this fantasy action-strategy game from Robot Entertainment.

Bumper Blitz TD redefines tower defense with gravity-powered physics and dynamic gameplay. Build, upgrade, and bounce enemies away in this thrilling fusion of strategy and action!

Rocked by an explosive soundtrack, choose your band, place your equipments and defend the Rock 'N' Roll from everyone and everything who try to pull it down, on a totally hardcore tower defense!

This is a sci-fi strategy game featuring a Defense Mode focused on tower defense and an Attack Mode focused on combat. The game includes over 30 different buildings and units, all of which can be upgraded through entry editing to enhance their performance and firepower.

Tower defense reimagined! Dead Ground is a procedurally generated tower defense game with rogue-like elements. Each playthrough will offer randomly generated guns, skills and augments. You'll have to travel, collect scrap, water, manage your inventory and upgrade your base to survive!

You believed tower defense is only about building towers? That's not quite right – because AIRA VR is not like other tower defense games in virtual reality. Once the battle starts you find yourself in the midst of the fight!

Celestial Defense is a sci-fi space tower defense strategy game where tactical base building and resource management determine your survival. Build asteroid belts, evolve planets, and withstand relentless wave survival combat against the Void.

The ultimate mash-up of Real-time Strategy and Tower Defense!

Mechs V Kaijus is an addictive hardcore tower defense gameplay. In Mechs V Kaijus you take on the role of Commander of a powerful Mechs squadron. Improve your Mech, strategically place towers and factories on the battlefield. Deploy support units on the battlefield, and save our civilization.

A 2D pixel art tower defense game with unparalleled strategic depth. Deploy modules to redirect enemies, use tactical chips to command the battlefield, and upgrade towers with multi-branch modifications to protect humanity's vital Stellacore energy.

Sci-fi Tower Defense real-time strategy with pleasant adaptive music. Play as a commander of a space station which got stuck in a time anomaly.

Celestial Wardens is a sci-fi tower defense game where you command a lone spaceship to defend a planet under siege. Survive waves of enemies, build turrets, upgrade your ship, and manage your planet to prevent total annihilation.

Gear up and get going! Defend your outposts from waves of alien enemies with your mech. Build and upgrade your base, protecting the extraction of the mysterious planetary system’s rich resources!

You think Tower Defense games are all about building? You thought wrong. Sanctum is not your average Tower Defense title. When the havoc starts, you get to join the fray! As one of the world’s first First Person Shooter - Tower Defense games, Sanctum has taken the best of both worlds to deliver an epic, one-of-a-kind experience.

A strategic space tower-defense game. Enemies detect, warn, and try to bypass defenses, forcing you to adapt. Combine diverse towers and face unique maps for varied battles. With tense sci-fi atmosphere, it delivers a fresh experience beyond traditional tower defense.

Space debris is out of control! Craft a station to take out the trash in this construction roguelite mashup.