Top similar games like PHYSARUM: Slime Mold Simulator:

Create and destroy on a scale you’ve never imagined!

The Sapling is a short simulation game where you design your own plants and animals, and put them in a world together. Or you turn on random mutations, and see what evolution does to your ecosystem!

Grow fluorescent cells that create mesmerizing emergent chaos. Simple mechanics hide deep complexity as cells evolve survival strategies through synergistic interactions. Catalogue successful lines and culture them to develop your own unique biology.

Enter the ambient world of Osmos: elegant, physics-based gameplay, dreamlike visuals, and a minimalist, electronic soundtrack. Your objective is to grow by absorbing other motes. Propel yourself by ejecting matter behind you. But be wise: ejecting matter also shrinks you. Relax - good things come to those who wait.

Falling-sand sandbox game with 500+ elements, chemistry, fire, life, food, and anything you can imagine.

Paint 27 kinds of matter. Set it on fire. Then press rewind. SunaBox is a physics sandbox in the spirit of the legendary OE-CAKE, on a bit-exact engine: every session can be replayed, rewound, saved, and shared to reproduce your world perfectly.

Dive into a world of creation and discovery, where each element combines to form new ones. Experiment freely in this interactive sandbox. But be careful: every combination has its consequences..

Jingjie is a strategy-simulation sandbox where you write laws, shape probability clouds, and guide a living world with embedded local AI. Observe, experiment, and watch complex life emerge from logic, tension, and chaos.

Dynamic abstract sandbox universe. Changes and evolves as you do.

"Falling sand" style particle sandbox, now with circuits and stickmen!

Graviton is a falling sand simulator in which you define your own interactive sand art. Sit back, relax, and draw from existing sand materials. Or take time to learn and create your own sands with complex rules. The possibilities are endless!

Seed, Breed, Create. From single cell organisms to complex ecosystems. Evolve every part of your own unique aquarium / terrarium by applying scientifically accurate principles of natural and artificial selection, in Creatura - ultimate Virtual Evolution Vivarium Simulator.

Eureka! Superconductor Lab is a crafting+simulation game where you synthesize materials and witness the astonishing scientific phenomena. Work alongside scholars, science geeks, and your girlfriend to synthesize the Holy Grail of modern physics: a room-temperature superconductor!

In Reus, you control powerful giants to shape the planet to your will. You can create mountains, oceans, forests and more. Enrich your planet with plants, minerals and animal life. There is only one thing on the planet that you do not control: mankind, with all their virtues and and all their vices.

“Escape the Lab” – Virtual Reality experience of an Escape Room that focuses on realistic chemical experiments.

Space Simulator and Music Machine!

Play with evolution! Species: ALRE is a scientifically-grounded, emergent simulation of natural selection. Creatures evolve and speciate in response to in-game mutation and selection forces, allowing you to experience and tinker with evolution in real-time.

Are you looking for something completely different? An oddity? An enigma? Or perhaps .. an Anomaly? Anomalies may be a game, then again it may not. One user described it as "A million musical leeches, waiting to suck the serotonin from my brain." And that's just the beginning...

Click to place components to create anything from a piano to a computer in a virtual sandbox environment.

Shape breathtaking worlds in Terra Firma 2, a vast simulation where your creations evolve through the forces of nature. Sculpt the land, then watch as weather, erosion, and life itself transform your world into a dynamic, living ecosystem- right down to every plant and creature.

Light, darkness and remarkable puzzles! Bend the light to your will in this award winning physics-based puzzle game. Feel like a renaissance engineer, build your own solutions to light puzzles, feel your brain grow and all of that within the beautiful and mysterious world of LIT.

Protect the environment, and save it from harm! Give commands to the animals, observe their rituals and help them survive. Face different disasters, react to human presence and help the animal kingdom flourish in this unique, environmental experience!

The world's first science-based photorealistic interactive 3D planetarium that models the entire Universe, using procedural generation for uncharted areas.

Gridworld is an artificial life and evolution simulator. Watch creatures evolve through natural selection as they learn to find food, avoid danger, and compete with other creatures for survival.

The epic story of evolution, technology, humanity, and dinosaurs is yours to tap.

Gene Evolution is a game that simulates the microscopic world. You can design unique cells, edit their attributes, functions, and intelligence. Then release them into the microscopic world and watch them forage, reproduce, compete, and continually evolve through mutations.

Build your dreams in this polyrhythm designer. Polyrhythm Lab is all about crafting relaxing or chaotic melodies, which can be played out for hours on end.

Create & destroy on an unimaginable scale with a realistic physics-based space simulator. Explore the beauty of our universe and the fragility of our planet. Use science to bend the laws of gravity, collide planets, boil away oceans, fire epic space lasers, and customize your universe.

A creative sandbox simulation where you experiment with physical interactions, build structures, and observe emergent behaviors in a world fully under your control.

Practice Alchemistry, aka the art of merging elements to discover new ones! Solve challenges or play freely to discover every element. Craft the entire world from fire to life.

An evolution simulation game. Take control of your species in the environment and edit your species as a whole. Compete with other evolving species for resources on an alien planet.

Get ready for conquering the world as a God! Show compassion to those who have nothing and they will love you. Take from those who have everything and they will fear you. Gain worshipers, fight skepticism and make the Earth belong to the gods once again! Long live the Greek Gods!

Create and evolve your own digital lifeforms! Watch or interact as your creations adapt and thrive in a world governed by the laws of physics. Download now and start your own evolutionary journey!

COVID SIMULATOR is an outbreak simulation that visualizes how quickly Covid-19 spreads, becoming a disaster. The game is an open sandbox where you can add (or remove) Covid mandates and see what happens! Create your workplace, enact your mandates, and roll the dice with your workers.

Tandis is a puzzle game where you discover mind-bending geometric shapes.

Build the most advanced operating system ever created! Can you master the fictional simulation language of this mind-bending machine? Design circuits, automate UBITS (coloured mobile data blocks), and optimize your system. The Admin is always watching, and he’s not what he seems.