Top similar games like PHYSARUM: Slime Mold Simulator:

Create and destroy on a scale you’ve never imagined!

The Sapling is a short simulation game where you design your own plants and animals, and put them in a world together. Or you turn on random mutations, and see what evolution does to your ecosystem!

Create & destroy on an unimaginable scale with a realistic physics-based space simulator. Explore the beauty of our universe and the fragility of our planet. Use science to bend the laws of gravity, collide planets, boil away oceans, fire epic space lasers, and customize your universe. VR optional.

Dynamic abstract sandbox universe. Changes and evolves as you do.

Seed, Breed, Create. From single cell organisms to complex ecosystems. Evolve every part of your own unique aquarium / terrarium by applying scientifically accurate principles of natural and artificial selection, in Creatura - ultimate Virtual Evolution Vivarium Simulator.

Space Simulator and Music Machine!

Graviton is a falling sand simulator in which you define your own interactive sand art. Sit back, relax, and draw from existing sand materials. Or take time to learn and create your own sands with complex rules. The possibilities are endless!

The world's first science-based photorealistic interactive 3D planetarium that models the entire Universe, using procedural generation for uncharted areas.

This is a beautiful "Idle", "Incremental" game based on spirals and mathematics. Your goal is to make the spiral grow farther and farther from the origin. The game is very simple, but it is very deep and can be enjoyed for a long time!

An evolution simulation game. Take control of your species in the environment and edit your species as a whole. Compete with other evolving species for resources on an alien planet.

Protect the environment, and save it from harm! Give commands to the animals, observe their rituals and help them survive. Face different disasters, react to human presence and help the animal kingdom flourish in this unique, environmental experience!

Vilmonic is an artificial life simulator and genetics and evolution sandbox game. Protect and breed unique pixel-art life forms where pixels and color have meaning. Craft tools and buildings and change the environment. Find ancient tech and fend off haywire zombitons. Craft Farm Breed Evolve!

Manipulate climate, add plants and evolve creatures in this planet and life sandbox simulation game. From cells to civilisations, spread life throughout the whole planet. Or just enjoy watching your creation burn!

A toy ecosystem with fully simulated genetics and evolution. Will you tinker with DNA or sit back, relax, and see if life finds a way?

Cells is a clicker idle game set in the world of microbiology. Take on the role of a scientist and experiment with digital single-celled organisms as they interact and evolve based on realistic physics and genetics.

The Magic Kaleidoscope is an amazing anti-stress coloring game where you can become the creator of your own magical textures and animations.

Be the Universe in this epic, award-winning reality simulation game - featuring thousands of playable characters, endless exploration, an extraordinary soundtrack and narration from Alan Watts.

Intervene in the evolution of virtual lifeforms that learn to move in a world powered by a physics engine. This world already features built-in mechanisms like heredity and natural selection. The player acts as a creator, manipulating these natural processes to help lifeforms learn and evolve.

You play as a scientist who is shrinking every second in a race against time! Find all the ingredients and formulas scattered around the laboratory, which are necessary for producing the life-saving antidote.

Play with evolution! Species: ALRE is a scientifically-grounded, emergent simulation of natural selection. Creatures evolve and speciate in response to in-game mutation and selection forces, allowing you to experience and tinker with evolution in real-time.

Create and evolve your own digital lifeforms! Watch or interact as your creations adapt and thrive in a world governed by the laws of physics. Download now and start your own evolutionary journey!

The epic story of evolution, technology, humanity, and dinosaurs is yours to tap.

Are you looking for something completely different? An oddity? An enigma? Or perhaps .. an Anomaly? Anomalies may be a game, then again it may not. One user described it as "A million musical leeches, waiting to suck the serotonin from my brain." And that's just the beginning...

Click to place components to create anything from a piano to a computer in a virtual sandbox environment.

A calm creative experience where you guide the development of an alien ecosystem. Study the environment and discover what drives it, or just sit back, relax, and see what happens!

Satellite Command is a realistic, relaxing astrophysics simulator. Complete contracts with real data, launch and take control of ever more powerful Satellites, research advanced technology and build your Space Agency!

Explore real digital life in The Bibites! Play god as you guide your bibites on their evolutionary journey. Analyze their Neural Network brains and genetic information as they adapt to their environments. Save your favorites and test their strength in Challenge Mode!

Have you ever wondered what the whole Universe looks like? With the myriad Galaxies, each containing billions of Stars, including our Solar System? Have you seen a Human Brain and its Neurons? DNA? What about the Electrons surrounding the tiny Atomic Nucleus? And what lies at even smaller scales?

EcoGenesis is a 2D black-box ecosystem simulator where you need to craft an ecosystem that can withstand the test of time. You must unlock creatures and balance your environment while driving towards one of the three victory conditions in this turn-based simulation.

Conductor is an audiovisual experience creation engine that encourages you to craft, save, and share funky environments with its vibrantly creative tool-set alongside all of your favorite media.

Strategy game about genes and animal species. Evolve, reproduce, expand to new territories, survive, and fight to achieve various goals like biodiversity or dominance in the ecosystem.

Just stop and relax. Forget about all the fuss and feel the magic of music in this game. Four different modes.

A brain-twisting blend of strategy and math where you compete against players across the globe.

An accurate simulation and visual representation of the spread of COVID in a supermarket, where the user can choose various simulation parameters such as amount of shoppers, if masks are worn, if people are vaccinated etc..

“Escape the Lab” – Virtual Reality experience of an Escape Room that focuses on realistic chemical experiments.