Top similar games like Chemistower:

Bioguard is a tower defense roguelite with a biological theme. Help the immune system using a variety of towers, skills and special cards. Develop your strategy to protect your body from invading pathogens and prevent their passage to vital organs!

Keyclash is a simple tower defense roguelike about building on keyboard keys and surviving as long as possible.

Atmospheric unique minimalist tower base defense game. Highly addictive.

Life on the Edge is an educational tower defense game. You play as a cell struggling to survive waves of bacteria and the COVID-19 virus. Protect your cell and build an understanding of cell biology at the same time!

A Tower Defense game mashed with Idle Clicker mechanics set inside a wonderful world of crayons. Build out your defenses, go grab a snack and watch your forces take on enemy units.

Laser Defense Extreme is a Tower Defense Game, with a Killstreak System. Place your "Towers" strategically and eliminate the incoming enemies.

This game is a arcade block placing game mixed with action-packed Tower Defense gameplay mechanics. Build forts out of tetrominoes high up in the sky and defend it against the incoming waves of airships, by shooting at them with your minigun and building defenses!

Node Math is a simple, idle-factory game about combining numbers with math operators, unlocking new stuff, and making money go brrr!

Beltmatic is a casual factory game where you combine numbers using mathematical operations.

One More Turret is an automation and tower defense strategy game with interesting innovations. Gather resources and enemy loot to construct intricate factory while defending against relentless monster waves. Can you strike the perfect balance between production and defense?

Use your special ops units to construct base facilities and towers to protect them from the ever-increasing threat of alien invaders in this Tower Defense game with a city-building element! Research their weaknesses and develop defenses before mankind runs out of time.

This is an RTS game less than 300MB, but it already contains many interesting game mechanics, There are many types of soldiers and tactics for you to choose. Support LAN online battle. Special Thanks for Pixel Art <Tiny Swords> UwU~ I hope you will be interested in more RTS games after playing :)

Become a Tsar! Create your own settlement and expand it into a stronghold to protect your people in a handcrafted side-scroller pixel art adventure game. Construct your town, gather resources, and fight enemies like a real tsar.

Build towers and learn abilities to defend against swarms of hundreds of on-screen hostile alien creatures. Choose between sets of randomized upgrades that both upgrade you and the alien swarm. From enormous explosions to far-reaching flamethrowers, no two games are the same.

Kaiju Commander is a strategy game where your main task is to dominate the whole world. To achieve this goal, you will be managing an evil corporation that breeds powerful monsters known as Kaiju. Develop your underwater base, gather resources, and dominate the world!

Tower Alchemy is a classic Tower Defense game with a twist. Mix and match your basic towers to unlock new powerful combinations from laser cannons and rail guns to meteor swarms and lightning bolts!

Engineered to Purpose is a new tower defence game where you custom-design towers to defend your base, with millions of builds to explore and refine. Set in the far future, E2P's story of posthumanism, family, and change will open new worlds to explore and survive.

Strategically build impenetrable towers & defenses, to endure the endless foes that emerge in the shroud of night. Each passing day is an opportunity to grow stronger. so take what you need from the environment. Gather, Craft, Survive, Defend, Thrive!

Build & defend a small remote mining base on Taichin XI from the alien hordes. Deploy defenses, upgrade your turrets and get ready for the nightfall. The Unearthened is a classic Idle Tower Defense game where you build towers and prepare for the invasion.

Beltex is a casual factory game played on a hex map. Extract numbers. Combine them using mathematical operations. Deliver them using belts across a huge map. Unlock new buildings and upgrades.

A Byte War is a real time strategy game where you lead a race of block-based machines against a machine threat from another dimension. Construct buildings from blocks arranged in various patterns and leverage your machines to convert the world around you.

SUPRACORE is a roguelike base building game. Build your base, upgrade it and defend against ongoing waves of enemies to gather more resources and expand your Core!

Defend your Nexus by placing mirrors and buildings on the path of your projectiles. Deflect, empower, manage and solve each map using your creative and strategic mind.

Step into the world of Defend from Candyland! where retro tower defense meets strategic depth. Plant and upgrade trees, use powerful buffs, and reveal enemy paths to shield Eden from waves of candy invaders. Master the challenge now!

Infinitode 2 - a strategy in the Tower Defense genre, in which the player will have to build towers to protect his base from endless waves of enemies. The game features huge maps, lots of towers, resource miners, upgrade tree and map editor.

Survive and evolve as an organism with this simulation game in which you will literally start as a single cell and manage and organize all its functions to a fully fledged system! Assemble, breathe, eat, fight threats, produce energy, grow, anything is possible!

Upgrade and evolve, expand your territory, and build mighty defense towers to repel hordes of monsters.

Paper Castle is a minimalist strategy game where you build, paint, and defend your kingdom of paper. Harness the power of water to protect it from relentless flames and enemy hordes. Will your Paper Castle survive the next wave?

Do you like Tower Defense games with Strategy elements? Well, look no further! We've got exactly what you're looking for! Get ready to defend your settlement from enemies using a huge arsenal of towers!

Gattai TD is a roguelike, mazing tower defense in which you merge towers and gain ancient wonders to hold back waves of cursed keepsakes.

Islets Defense is a turn-based tower defense game in which you build a small village to gather resources and defend your castle. Carefully plan your actions, as each move brings the enemy waves closer! Strategize building placements and play your cards wisely, as timing and order are key.

Design increasingly complex computation units powered by high pressure steam. From switches to steam based computers, all in a world of analogue pressure devices. Use previous designs to solve further challenges, unravel the mystery of the missing steam and discover a new field of science.

Planet Gemini is a factory building and tower defense game. On two planets that crash-landed during a dimension trip, survive against incoming enemies and research on a portal to escape.

A game of base building and colony simulation in a world where night is permanent. Survive, build, explore, repel enemy raids and tend to the needs of your workers and your king.

Snacktorio is a factory-cooking simulator where you must satisfy the appetites of unspeakable horrors... with food! Build and manage sprawling networks of machines & pipes to mass produce delicious meals that can satiate the endless hunger of the beasts that are invading your home. Order Up!