Top similar games like Chemistower:

Bioguard is a tower defense roguelite with a biological theme. Help the immune system using a variety of towers, skills and special cards. Develop your strategy to protect your body from invading pathogens and prevent their passage to vital organs!

Keyclash is a simple tower defense roguelike about building on keyboard keys and surviving as long as possible.

Become a Tsar! Create your own settlement and expand it into a stronghold to protect your people in a handcrafted side-scroller pixel art adventure game. Construct your town, gather resources, and fight enemies like a real tsar.

HEARTHWATCH is a neon tower defense roguelite where the map tears open mid-battle. Hold the Hearth against the Ashen: fuse elements into hybrids, draft a deck built for the age you are in, and rebuild your line when a new lane grows across the board.

Life on the Edge is an educational tower defense game. You play as a cell struggling to survive waves of bacteria and the COVID-19 virus. Protect your cell and build an understanding of cell biology at the same time!

Build, automate, and defend humanity's last factory on a dying industrial planet. Chain production lines, survive AUTON raids and dust storms, research lost technology, and uncover what silenced every factory before yours.

Laser Defense Extreme is a Tower Defense Game, with a Killstreak System. Place your "Towers" strategically and eliminate the incoming enemies.

A Tower Defense game mashed with Idle Clicker mechanics set inside a wonderful world of crayons. Build out your defenses, go grab a snack and watch your forces take on enemy units.

This game is a arcade block placing game mixed with action-packed Tower Defense gameplay mechanics. Build forts out of tetrominoes high up in the sky and defend it against the incoming waves of airships, by shooting at them with your minigun and building defenses!

Node Math is a simple, idle-factory game about combining numbers with math operators, unlocking new stuff, and making money go brrr!

One More Turret is an automation and tower defense strategy game with interesting innovations. Gather resources and enemy loot to construct intricate factory while defending against relentless monster waves. Can you strike the perfect balance between production and defense?

Stranded on a floating island in the shadow of a mysterious cube planet, you must survive using only your wits and advanced engineering. Build intricate automation lines, manage power grids, and transform a single tree into a sprawling industrial space station. Will you find your way home?

Beltmatic is a casual factory game where you combine numbers using mathematical operations.

Use your special ops units to construct base facilities and towers to protect them from the ever-increasing threat of alien invaders in this Tower Defense game with a city-building element! Research their weaknesses and develop defenses before mankind runs out of time.

Atmospheric unique minimalist tower base defense game. Highly addictive.

Build production lines to extract resources, craft parts, and assemble towers. Complete orders, earn rewards, unlock new machines, and grow your factory.

Hoard Buttons and keep them safe from stealing gnomes. Get those Buttons Up by crafting buildings, trading with merchants and by travelling to weird biomes for rare resources. Unlock new skills with prestige points and become the button master in this chill survival incremental game.

Power the Unknown is a strategy game where you build a base on an unexplored planet and defend it from swarms of hostile bugs. Mine resources and generate enough energy to power your ever-growing base.

This is an RTS game less than 300MB, but it already contains many interesting game mechanics, There are many types of soldiers and tactics for you to choose. Support LAN online battle. Special Thanks for Pixel Art <Tiny Swords> UwU~ I hope you will be interested in more RTS games after playing :)

Build towers and learn abilities to defend against swarms of hundreds of on-screen hostile alien creatures. Choose between sets of randomized upgrades that both upgrade you and the alien swarm. From enormous explosions to far-reaching flamethrowers, no two games are the same.

Kaiju Commander is a strategy game where your main task is to dominate the whole world. To achieve this goal, you will be managing an evil corporation that breeds powerful monsters known as Kaiju. Develop your underwater base, gather resources, and dominate the world!

Tower Alchemy is a classic Tower Defense game with a twist. Mix and match your basic towers to unlock new powerful combinations from laser cannons and rail guns to meteor swarms and lightning bolts!

Engineered to Purpose is a new tower defence game where you custom-design towers to defend your base, with millions of builds to explore and refine. Set in the far future, E2P's story of posthumanism, family, and change will open new worlds to explore and survive.

An idle defense game at the bottom of your screen. Build your squad, upgrade your base, and hold the line against relentless alien waves while you work or browse.

Strategically build impenetrable towers & defenses, to endure the endless foes that emerge in the shroud of night. Each passing day is an opportunity to grow stronger. so take what you need from the environment. Gather, Craft, Survive, Defend, Thrive!

A Byte War is a real time strategy game where you lead a race of block-based machines against a machine threat from another dimension. Construct buildings from blocks arranged in various patterns and leverage your machines to convert the world around you.

Idle defense you can't lose meets conveyor-belt factory automation. Your bunker holds back an endless swarm, every kill drops raw materials into the warehouse, then belts haul them to production lines you design, turning bugs into ammo, lures and goods. More bugs, more resources, a bigger factory.

Build & defend a small remote mining base on Taichin XI from the alien hordes. Deploy defenses, upgrade your turrets and get ready for the nightfall. The Unearthened is a classic Idle Tower Defense game where you build towers and prepare for the invasion.

SUPRACORE is a roguelike base building game. Build your base, upgrade it and defend against ongoing waves of enemies to gather more resources and expand your Core!

Flowchart is your weapon. Recursion is a strategy game merging logic circuit design with tower defense. architect their paths, and defend the system by engineering the perfect logic loop with maximum efficiency.

Beltex is a casual factory game played on a hex map. Extract numbers. Combine them using mathematical operations. Deliver them using belts across a huge map. Unlock new buildings and upgrades.

You are a dendritic cell. Rally neutrophils, charge into bacteria, carry antigen to the lymph node and craft antibodies. A roguelike blend of RTS and tower defense that follows one patient's immune system from age 2 to 72 — built on real immunology.

Defend your Nexus by placing mirrors and buildings on the path of your projectiles. Deflect, empower, manage and solve each map using your creative and strategic mind.

Freely place a 15-chassis defense network, break visible enemy layers, and time Flux Gates, Protocol choices, commander abilities, and Overdrive across a 20-mission neon tower defense campaign.

Step into the world of Defend from Candyland! where retro tower defense meets strategic depth. Plant and upgrade trees, use powerful buffs, and reveal enemy paths to shield Eden from waves of candy invaders. Master the challenge now!

A maze-building tower defense against hordes of thousands. Raise walls, build 15 kinds of defenses, pick a card every wave and unlock a 562-upgrade skill tree. Slow-motion missiles, a boss every wave and endless waves: how far can you go?