Top similar games like Chemistower:

Bioguard is a tower defense roguelite with a biological theme. Help the immune system using a variety of towers, skills and special cards. Develop your strategy to protect your body from invading pathogens and prevent their passage to vital organs!

Keyclash is a simple tower defense roguelike about building on keyboard keys and surviving as long as possible.

Become a Tsar! Create your own settlement and expand it into a stronghold to protect your people in a handcrafted side-scroller pixel art adventure game. Construct your town, gather resources, and fight enemies like a real tsar.

Play as an evil god in this 2D top-down survival colony-defense roguelite. Defend your cult, satisfy your altar’s growing hunger for Meat sacrifice. Kill, harvest, process meat, optimize production, and survive as long as you can.

Life on the Edge is an educational tower defense game. You play as a cell struggling to survive waves of bacteria and the COVID-19 virus. Protect your cell and build an understanding of cell biology at the same time!

Build, automate, and defend humanity's last factory on a dying industrial planet. Chain production lines, survive AUTON raids and dust storms, research lost technology, and uncover what silenced every factory before yours.

Laser Defense Extreme is a Tower Defense Game, with a Killstreak System. Place your "Towers" strategically and eliminate the incoming enemies.

A Tower Defense game mashed with Idle Clicker mechanics set inside a wonderful world of crayons. Build out your defenses, go grab a snack and watch your forces take on enemy units.

This game is a arcade block placing game mixed with action-packed Tower Defense gameplay mechanics. Build forts out of tetrominoes high up in the sky and defend it against the incoming waves of airships, by shooting at them with your minigun and building defenses!

Node Math is a simple, idle-factory game about combining numbers with math operators, unlocking new stuff, and making money go brrr!

One More Turret is an automation and tower defense strategy game with interesting innovations. Gather resources and enemy loot to construct intricate factory while defending against relentless monster waves. Can you strike the perfect balance between production and defense?

Beltmatic is a casual factory game where you combine numbers using mathematical operations.

Use your special ops units to construct base facilities and towers to protect them from the ever-increasing threat of alien invaders in this Tower Defense game with a city-building element! Research their weaknesses and develop defenses before mankind runs out of time.

Survive endless waves of dark entities, use your clicks as a resource, and grow stronger with every run. Find and upgrade powerful modules and unlock new technologies in this incremental clicker defense game. Also - Everything is square.

This is an RTS game less than 300MB, but it already contains many interesting game mechanics, There are many types of soldiers and tactics for you to choose. Support LAN online battle. Special Thanks for Pixel Art <Tiny Swords> UwU~ I hope you will be interested in more RTS games after playing :)

Build towers and learn abilities to defend against swarms of hundreds of on-screen hostile alien creatures. Choose between sets of randomized upgrades that both upgrade you and the alien swarm. From enormous explosions to far-reaching flamethrowers, no two games are the same.

Kaiju Commander is a strategy game where your main task is to dominate the whole world. To achieve this goal, you will be managing an evil corporation that breeds powerful monsters known as Kaiju. Develop your underwater base, gather resources, and dominate the world!

An idle defense game at the bottom of your screen. Build your squad, upgrade your base, and hold the line against relentless alien waves while you work or browse.

Tower Alchemy is a classic Tower Defense game with a twist. Mix and match your basic towers to unlock new powerful combinations from laser cannons and rail guns to meteor swarms and lightning bolts!

Engineered to Purpose is a new tower defence game where you custom-design towers to defend your base, with millions of builds to explore and refine. Set in the far future, E2P's story of posthumanism, family, and change will open new worlds to explore and survive.

Strategically build impenetrable towers & defenses, to endure the endless foes that emerge in the shroud of night. Each passing day is an opportunity to grow stronger. so take what you need from the environment. Gather, Craft, Survive, Defend, Thrive!

Build & defend a small remote mining base on Taichin XI from the alien hordes. Deploy defenses, upgrade your turrets and get ready for the nightfall. The Unearthened is a classic Idle Tower Defense game where you build towers and prepare for the invasion.

A Byte War is a real time strategy game where you lead a race of block-based machines against a machine threat from another dimension. Construct buildings from blocks arranged in various patterns and leverage your machines to convert the world around you.

SUPRACORE is a roguelike base building game. Build your base, upgrade it and defend against ongoing waves of enemies to gather more resources and expand your Core!

Flowchart is your weapon. Recursion is a strategy game merging logic circuit design with tower defense. architect their paths, and defend the system by engineering the perfect logic loop with maximum efficiency.

Beltex is a casual factory game played on a hex map. Extract numbers. Combine them using mathematical operations. Deliver them using belts across a huge map. Unlock new buildings and upgrades.

Defend your Nexus by placing mirrors and buildings on the path of your projectiles. Deflect, empower, manage and solve each map using your creative and strategic mind.

Hex Tower Boogie is a tower defense game about stacking absurd combos. A cannon that one-shots everything every 10 seconds? Sure. A homing splash tower? Take it. Homing + multishot + piercing + bonus damage on one bullet? ...yeah, you can have that too.

Step into the world of Defend from Candyland! where retro tower defense meets strategic depth. Plant and upgrade trees, use powerful buffs, and reveal enemy paths to shield Eden from waves of candy invaders. Master the challenge now!

Pelikeeper is a tower defense & base building comfort-strategy game where you play as the last pelican in a world swallowed by a shadowy fog. Build up and defend the settlement around your lighthouse, rescue lost animal neighbors, and return constellations to the cosmos.

Infinitode 2 - a strategy in the Tower Defense genre, in which the player will have to build towers to protect his base from endless waves of enemies. The game features huge maps, lots of towers, resource miners, upgrade tree and map editor.

Survive and evolve as an organism with this simulation game in which you will literally start as a single cell and manage and organize all its functions to a fully fledged system! Assemble, breathe, eat, fight threats, produce energy, grow, anything is possible!

Find the best island, outbid your rivals and start exploiting it. Automate your production and watch the market to sell your goods at the right price. Use your profits to buy upgrades and make your production chain even faster.

Upgrade and evolve, expand your territory, and build mighty defense towers to repel hordes of monsters.

Place magical constructs around a swirling cosmic rift, chain together exotic energies, and collapse reality to grow stronger in this deep incremental game.

Stranded on a floating island in the shadow of a mysterious cube planet, you must survive using only your wits and advanced engineering. Build intricate automation lines, manage power grids, and transform a single tree into a sprawling industrial space station. Will you find your way home?